Chemicals and Drugs | Dermatology | Medicine and Health Sciences | Neoplasms
Background: Zone based photodynamic therapy (PDT) is a promising treatment option for actinic keratosis, superficial basal cell carcinoma, and in-situ squamous cell carcinoma. PDT has similar cure rates to 5-fluorouracil and imiquimod. Objective: Determine if PDT zone treatments improve patient comfort, tolerance, retention, and offer less severe reactions as compared to full face treatments. Methods: 500 PDT patients were divided into full face (n = 250) versus zone treatments (n = 250). All subjects completed a post-treatment phone survey assessing tolerance of procedure. Retention rates and severe reactions were tracked. Results: Zone treatment resulted in a higher number of excellent responses for patient tolerance vs. full face treatment group (85 % vs. 39%, P
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Aleshaki, Joseph OMS-II and Crawford, Dr. Kevin, "Comparison of Patient Tolerance of Photodynamic Therapy with Zone vs. Full Face Treatment" (2015). MU-COM Research Day. 8.