A 3D Visualization of Depression and Anxiety

Faculty Advisor

David L. Dufeau Ph.D

Document Type


Publication Date



Medicine and Health Sciences


The goal of this project is to build a teaching tool geared towards patients, students, and clinicians to further educate themselves about the anatomical and biochemical implications of various syndromes involving depression and anxiety. Secondarily, we also want to inform patients, students, and clinicians about the most common treatment methods used to treat these syndromes. We achieved this by mapping the mesolimbic system and other relevant neuroanatomical structures using a high-resolution cryosec-tion dataset made available by the Big Brain project at McGill University using cutting-edge 3D analysis software tools. The results of this project were compiled into a series of three videos serving each of the goals. The first video described the neuroanatomical structures involved in syndromes of depression and anxiety along with their functions. The second video describes various forms of clinical depression and treatment options, including the mechanism of action and how it applies to the underlying disease process. The third video did the same but described anxiety rather than depression. This tool we developed is important because it explains neuroanatomical and biochemical aspects of these syndromes in a straight-forward and easy-to-understand visual manner. It also describes the context of the best pharmacological interventions for each syndrome, which is a substantial step to help engage patients in their personalized mental health treatment plan.


Copyright 2019 all authors

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