Background We present 3 likely cases of testicular dysgenesis syndrome (TDS) within a community of chimpanzees (Pan troglodytes schweinfurthii). We tested whether genetic drift may be the culprit, as a genetic cause has been suspected to account for TDS among other wildlife. Methods: We successfully sequenced a 367?bp segment spanning the first hypervariable region within the D?loop of the mitochondrial genome for 78 DNA samples. Results: We found 24 polymorphic sequence sites consisting of 7 singletons and 17 parsimony informative sites. This sample contained 9 haplotypes with a diversity index of 0.78 (SD = 0.03). All tests against the null hypothesis of neutral polymorphisms were non?significant (P > .10). The mismatch distribution of pairwise differences does not fit a Poisson's curve (raggedness index = 0.166; SSD = 0.12; P = 1). Conclusions: Thus, we found no significant signs of genetic isolation, population expansion, or genetic bottleneck. Alternative causes of TDS and how they might pertain to this population are discussed.

Creator

• Rich, Alicia M.

• Hunt, Kevin D.

• Breeden, Scott K. OMS-4

• Wasserman, Michael D.

• Kaestle, Frederika

• Deimel, Caroline

Language

• English

Identifier

• https://doi.org/10.1111/jmp.12352

Palavra-chave

• Primatology

• Testicular Dysgenesis Syndrome

• Chimpanzees

Date created

• 5/25/2018

Related URL

• Full Text available at the following URL:  https://onlinelibrary.wiley.com/doi/abs/10.1111/jmp.12352

Resource type

• Article

Source

• Journal of Medical Primatology

• mucom_spr_27

Rights statement

• http://rightsstatements.org/vocab/InC/1.0/