Is Genetic Drift to Blame for Testicular Dysgenesis Syndrome in Semliki Chimpanzees (Pan Troglodytes Schweinfurthii)?
Público DepositedMLA citation style (9th ed.)
. 5252. mushare.marian.edu/concern/generic_works/aedaf7dc-5a6a-4c6e-beb1-58818560af37?locale=es. Is Genetic Drift to Blame for Testicular Dysgenesis Syndrome In Semliki Chimpanzees (pan Troglodytes Schweinfurthii)?.APA citation style (7th ed.)
(5252). Is Genetic Drift to Blame for Testicular Dysgenesis Syndrome in Semliki Chimpanzees (Pan Troglodytes Schweinfurthii)?. https://mushare.marian.edu/concern/generic_works/aedaf7dc-5a6a-4c6e-beb1-58818560af37?locale=esChicago citation style (CMOS 17, author-date)
Is Genetic Drift to Blame for Testicular Dysgenesis Syndrome In Semliki Chimpanzees (pan Troglodytes Schweinfurthii)?. 5252. https://mushare.marian.edu/concern/generic_works/aedaf7dc-5a6a-4c6e-beb1-58818560af37?locale=es.Note: These citations are programmatically generated and may be incomplete.
Background We present 3 likely cases of testicular dysgenesis syndrome (TDS) within a community of chimpanzees (Pan troglodytes schweinfurthii). We tested whether genetic drift may be the culprit, as a genetic cause has been suspected to account for TDS among other wildlife. Methods: We successfully sequenced a 367?bp segment spanning the first hypervariable region within the D?loop of the mitochondrial genome for 78 DNA samples. Results: We found 24 polymorphic sequence sites consisting of 7 singletons and 17 parsimony informative sites. This sample contained 9 haplotypes with a diversity index of 0.78 (SD = 0.03). All tests against the null hypothesis of neutral polymorphisms were non?significant (P > .10). The mismatch distribution of pairwise differences does not fit a Poisson's curve (raggedness index = 0.166; SSD = 0.12; P = 1). Conclusions: Thus, we found no significant signs of genetic isolation, population expansion, or genetic bottleneck. Alternative causes of TDS and how they might pertain to this population are discussed.
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Journal of Medical Primatology
mucom_spr_27
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