Faculty Publications and Research - MUCOM

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52 Items

Last Updated: 2022-04-01

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College of Osteopathic Medicine

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Articles au total: 52

Travaux (52)

31. Loss of BMPR2 Expression in Skeletal Progenitor Cells Reduces Age-Related Bone Loss

Créateur:: Newby, J.B., Lowery, Jonathan W., Rosen V., Hudnall, J.B., and Eaton, M.S.
Type:: Conference

32. Increased Susceptibility to Hypoxic Pulmonary Hypertension in Bmpr2 Mutant Mice is Associated with Endothelial Dysfunction in the Pulmonary Vasculature

Créateur:: de Caestecker, M., Frank, D.B., Lowery Jonathan W., Reese, J., Anderson, L., and Brink, M.
La description:: Patients with familial pulmonary arterial hypertension inherit heterozygous mutations of the type 2 bone morphogenetic protein (BMP) receptor BMPR2. To explore the cellular mechanisms of this disease, we evaluated the pulmonary...
Type:: Article

33. Bmp2 and Bmp4 Exert Opposing Effects in Hypoxic Pulmonary Hypertension

Créateur:: de Caestecker, M., Chandler, R.L., Mortlock, D.P., Anderson, L.A., Frank, D.B., Jones, M.T., and Lowery, Jonathan W.
La description:: The bone morphogenetic protein (BMP) type 2 receptor ligand, Bmp2, is upregulated in the peripheral pulmonary vasculature during hypoxia-induced pulmonary hypertension (PH). This contrasts with the expression of Bmp4, which is...
Type:: Article

34. BMP Signaling in Vascular Development and Disease.

Créateur:: de Caestecker, M. and Lowery, Jonathan W.
La description:: Genetic and functional studies indicate that common components of the bone morphogenetic protein (BMP) signaling pathway play critical roles in regulating vascular development in the embryo and in promoting vascular homeostasis...
Type:: Article

35. ID Family Protein Expression and Regulation in Hypoxic Pulmonary Hypertension

Créateur:: Frump, A.L., de Caestecker, M., Anderson, L.A., Lowery, Jonathan W, Jones, M.T., and diCarlo, G.E.
La description:: Bone morphogenetic protein (BMP) signaling has been linked to the development of pulmonary hypertension (PH). Inhibitors of differentiation (ID) proteins (ID1-4) are a family of basic helix-loop-helix transcription factors that...
Type:: Article

36. The Role of BMP2 Signaling in the Skeleton.

Créateur:: Intini, G., Lowery, Jonathan W., Rosen, V., Pazin, D., Chappuis, V., Capelo, L.P., and Kokabu, S
La description:: While new roles for the adult skeleton as an endocrine organ continue to emerge, our understanding of how bone homeostasis is maintained is also changing. Here we focus on BMP2, a molecule identified by its ability to induce...
Type:: Article

37. BMPR-II is Dispensable for Formation of the Limb Skeleton.

Créateur:: Beppu, H., Lowery, Jonathan W., Rosen, V., Tsuji, K., Cox, K., Capelo, L.P., and Gamer, L.W.
La description:: Initiation of BMP signaling is dependent upon activation of Type I BMP receptor by constitutively active Type II BMP receptor. Three Type II BMP receptors have been identified; Acvr2a and Acvr2b serve as receptors for BMPs and...
Type:: Article

38. Allele-specific RNA Interference in FOP Silencing the FOP Gene

Créateur:: Lowery, Jonathan W. and Rosen, V.
Type:: Article

39. BMP Signaling and Vascular Disease

Créateur:: de Caestecker, M. and Lowery, Jonathan W.
Type:: Article

40. BMP3 Suppresses Osteoblast Differentiation of Bone Marrow Stromal Cells Via Interaction With Acvr2b.

Créateur:: Lowery, Jonathan W., Rosen, V., Econimedes, A., Katagiri, T., Cox, K., Kunikazu, T., Kokabu, S, and Gamer, L.
La description:: Enhancing bone morphogenetic protein (BMP) signaling increases bone formation in a variety of settings that target bone repair. However, the role of BMP in the maintenance of adult bone mass is not well understood. Targeted...
Type:: Article