Calcitriol is a vitamin critical in regulating calcium
homeostasis, maintenance of musculoskeletal
integrity, and both a commonly prescribed medication
and over the counter supplement.
• However, the incidence of vitamin D...
Children with acute lymphoblastic leukemia
(ALL) suffer a litany of therapy induced side
effects. Methotrexate is a common chemotherapy agent
administered for the treatment of ALL. Failure to clear methotrexate from the body...
Multiple sclerosis (MS), one of the most
prevalent immune-mediated neurological
disorders, is a chronic demyelinating disease
of the central nervous system that affects both
white and grey matter (Avasarala et....
3D visualization software is a useful tool in
patient education because it allows patients to
put an image to what a physician is describing
to them. With an emphasis on education of
young athletes on the potential...
Klotho is a regulatory anti-aging protein that is significantly expressed
in the choroid plexus, plays an important role in regulating the immune
response in the CNS, and diminishes with age. Klotho deficiency is...
Kisspeptin together with its receptor, GPR54 (Kiss1R), are known for their function as the principal regulators of the onset of mammalian puberty. Given the characteristic growth spurt and bone development that occurs during...
Due to the availability of information on the internet, patients are well informed of the several types of hernia repair available to them. They are also increasingly made aware of the litigious environment surrounding...
Chlamydia trachomatis (Ct) is the most common bacterial sexually transmitted pathogen and is a significant threat to the reproductive health of women. With an estimated 2.8 million new infections domestically and 131 million...
Recent studies describe racial and socioeconomic
(SES) disparities with mechanical thrombectomy
(MT) for acute ischemic stroke (AIS). Our study
investigated whether such disparities are present at
our institution and...
Nursing Homes (NH) often struggle to provide
Palliative Care (PC) to their residents with Alzheimer’s
and other Related Dementias (ADRDs). As a result,
many NHs are searching for external PC consultants to
help facilitate...
Chemotherapeutic agents, such as vincristine, are well known
antineoplastic and cytotoxic drugs, affecting patients broadly during
treatment of cancer. Well known side effects, such as constipation
and neuropathic pain,...
The COVID-19 pandemic resulted in widespread mRNA vaccinations against SARS-CoV2. Side effects include fatigue, headache, myalgia,
fever, nausea, and lymphadenopathy, frequently experienced in younger recipients (16-55 years)...
Antibiotic resistance is not only a major threat to public health, with more than
700,000 deaths per year, but also has serious economic impacts.1 Nosocomial-
acquired antibiotic-resistant infections have well-established...
Bitter melon extract (BME) is known to inhibit breast cancer cells (MCF-7) proliferation. Due to the high metabolic rate of cancer cells, we hypothesized that low glucose levels are detrimental to cell survivability and that...
Older adults (65+) are at an increased risk of contracting COVID-19 and have higher incidences of adverse events. Nursing home residents are particularly vulnerable due to congregate living and the need for personal care. CMS...
Malignant mesothelioma typically presents in patients with asbestos exposure, with respiratory symptoms caused by primary pleural involvement with associated pleural effusion. Instead, this patient presented with a rapidly...
Ambulances are a target for theft and reportings of ambulance thefts has been increasing in the past several years. There is a paucity of research in this area, as a PubMed search of the terms ambulance theft yields only one...
Rubella was first described in the 1750s but took until 1941 when Congenital Rubella Syndrome was characterized to become medically significant. Similarly, zika virus was discovered in 1947 but only made headlines in 2016 when...
Reported cases of isolated fetal ascites determined to be idiopathic have been shown to carry a favorable prognosis with frequent spontaneous resolution in utero (1,2,3). These cases generally reported better fetal outcomes...
Over 1.25 million people reside in nursing facilities in the United States. Nursing facilities have reported 268,707 confirmed cases of COVID-19 and 61,765 COVID-19 deaths as of the week of November 2, 2020. Indiana was one of...
Osteoporosis is a silent, dangerous pathology frequently undiagnosed until patients experience a major fracture. About 1 in 2 women and 1 in 4 men ages 50 and above will experience bone fractures due to osteoporosis. Fractures...
Healthcare disparities among different racial and ethnic groups are prevalent across the United States and worldwide. Healthcare provision may differ among racial and ethnic minorities, socioeconomic statuses, and insurance...
The ability to communicate with patients effectively continues to be a major hindrance for physicians and physician offices. Coordinating care via conventional telecommunication, involving making calls to a healthcare facility...
The unique conditions of microgravity and radiation exposure in space have a substantial impact on human tissue function, resulting in extreme bone loss. The goal of this project is to synthesize the current knowledge on bone...
Previous studies indicate that common fibular, tibial, and radial skin sympathetic nerve activity (SSNA) increases with physical stress in an exercise intensity-dependent manner but abates during ischemia when class Ill & IV...
The COVID-19 pandemic has created a unique situation for medical education worldwide as traditional medical training is not compatible with social distancing guidelines. Curriculums, content delivery, and procedures across...
Head and neck squamous cell carcinomas (HNSCCs) have remained one of the common and lethal cancers around the world. HNSCC rapidly spread via the lymphatics system, leading to a higher percentage of initial late-stage diagnoses...
Acute cardiac injury is a common cardiovascular complication of Covid19 and little is currently known about the long term implications of the complications and manifestations. Vascular complications show a hypercoagulable state...
Multi-system disorders may be difficult to differentiate between,
especially as genetic causes are still being defined and in light
of phenotypic variability. We present a case of a teen with
multiple congenital defects for...
Traditional medical education has recently seen major changes due to the coronavirus (COVID-19) pandemic. New pedagogical methods, including augmented reality (AR} and virtual reality (VR), arc on the rise as alternatives to...
The history and use of virtual and augmented reality dates back to the early 19th Century, Charles Wheatstone an English scientist, and inventor discovered that the brain interrupts stereoscopic photos and paintings differently...
Introduction: Kisspeptin together with its receptor, GPR54 (Kiss1 R), are known for their function as the principal regulators of the onset of mammalian puberty. Given the characteristic growth spurt and bone development that...
• Traditional medical education typically consists of two years of didactic, lecture-based education {Years 1 and 2), as well as two years of clinical clerkships and patient interactions {Years 3 and 4)
Eccrine sweating glands are divided into functional units: I) a bulbous secretory coil that generates precursor fluid, and 2) a reabsorptive duct that transports the fluid to the skin surface. The secretory coils reside in the...
Multiple osteochondromas (MO) is a rare genetic disorder characterized by accessory bone growths usually stemming from the epiphyseal plate oflong bones. MO affects about l in 50,000 lirn births. Complications of MO include...
Diabetic ketoacidosis (DKA) is a life threatening complication of type 1 diabetes (T1D) resulting from ketone body production and metabolic acidosis occurring due to insulin deficiency, We sought to define the occurrence of DKA...
The proposed solution is a self-reported, symptoms-based syndromic surveillance system that is universal, interactive, integrative, and combined with artificial intelligence. Once developed, this framework has the potential to...
Brexanolone (ZULRESSO ™) is a novel approach to treat postpartum depression in adult women as a neuroactive steroid similar in chemical composition to the hormone allopregnanolone. It was approved for use in adult women...
Objecti ve: Soft tissue manual therapies are commonly utilized by osteopathic physicians, chiropractors, physical therapists and massage therapists. These techniques are predicated on subjecting tissues to biophysical...
Segmental bone defects secondary lo high-energy trauma may not spontaneousfy heal and orthopedic surgeons call on the use of bone graft substitutes. Bone morphogenetic prntein-2 (BMP-2) and thrombopoietin (TPO) are an FDA...
Book, presentation, and video are the current most popular modalities used
for grasping what is conceptual in OMM; Students entering medical school
have a higher degree of technological literacy. Education technology...