... activated B cells (NF-B) and other proinflammatory transcriptional 1 Department of Biology, Middle Tennessee ...
... ., 2010; Leopold Wager et al., 2014, 2015). This transition to the M1 state is accompanied by extensive ...
... transcriptional reprograming, involving over 1000 genes (Beyer et al., 2012; Jablonski et al., 2015). These ...
... activator of transcription 1 (STAT1) and interferon regulated factor 1 (IRF1), operating individually or in ...
... from dimers of IFNGR1 and IFNGR2. This activates receptor-associated Janus kinase (JAK) 1 and 2 by ...
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