Background: It has been observed that patients with poor mental health are relatively frequent users of the Emergency Departments (ED). The objective of this study was to evaluate the prevalence of numerous behavioral health...
Background: Due to globalization, spread of a pandemic is inevitable as we have seen with COVID-19. Further, increased ease of travel increases the potential and frequency of pandemics. Hence, it is imperative to find solutions...
"This chapter briefly traces the history of priestly celibacy in the Catholic Church, its reasons, and the crisis in vocations the discipline created, partly as a result of the Second Vatican Council’s praise of sexuality in...
The United States spends well over $100 billion for millions of people affected by Alzheimer’s disease and related dementias (ADRD) and for their family caregivers. Most people with ADRD have multiple chronic comorbid...
The chapter opens with a discussion of the Great Railroad Strike of 1877 in which questions regarding the social order, class, equity, and like matters arise. The coincidental arrival in Indianapolis of Denis Kearney and the...
Presented in the Innovative Assessment of Learning track. and MAT250 transitions students to advanced mathematics. Objectives include learning to justify mathematical statements using standard methods of proof and communicate...
Within the last quarter of the twentieth century and now well into the twenty-first, the historical novel has been a prolific and popular form in Spain for commentary on the dictatorship, the Transition and contemporary...
Background: The implementation of a standardized warming protocol aims to prevent hypothermia in the postoperative period. Hypothermia in the postoperative period can result in inadvertent adverse outcomes for patients...
Medication errors and interactions happen every day in the perioperative setting. It is the responsibility of the post-anesthesia care unit (PACU) nurse to manage pain, nausea, vomiting, and maintain hemodynamics after surgery...
Development of new and highly tailored chemotherapeutic agents continues to be the mainstay for innovative clinical treatment of cancer. Peroxisome proliferator-activated receptors (PPARs), part of a nuclear hormone super...
A presentation at the 2017 Higher Education Partnership: Internationalization in the Americas conference in San Miguel de Allende, Mexico (sponsored by the Partners of the Americas organization). This presentation outlines the...
<b>Background</b>: Many surgical procedures require muscle paralysis of the patient to ensure optimum operating conditions. Monitoring the level of paralysis is an important responsibility of the nurse anesthetist throughout...
The LGBT+ community is generally grouped into one big group with all the same needs by media, organizations, and people. However, LGBT+ people have different concerns and needs based on age, race, ability, and so many other...
This article is an invitation to Christian youth and young adult educators and ministers to be more understanding of queer theology and to discern its place within ministry to and for young people. The article examines the term...
Healthcare disparities among different racial and ethnic groups are prevalent across the United States and worldwide. Healthcare provision may differ among racial and ethnic minorities, socioeconomic statuses, and insurance...
Recent studies describe racial and socioeconomic
(SES) disparities with mechanical thrombectomy
(MT) for acute ischemic stroke (AIS). Our study
investigated whether such disparities are present at
our institution and...
Over 1.25 million people reside in nursing facilities in the United States. Nursing facilities have reported 268,707 confirmed cases of COVID-19 and 61,765 COVID-19 deaths as of the week of November 2, 2020. Indiana was one of...
Presented in the Active/Collaborative Learning track. and Student engagement and collaborative learning is enhanced by following the customized "Internship Playbook." A large population of the students in the School of Business...
This article discusses the collaborative digitization effort between librarians at Marian College (now Marian University) and Indiana University Purdue University Indianapolis (IUPUI) to create a deliverable online collection...
We argue that one of the best ways to improve equity and diversity in the plant sciences begins in the undergraduate
classroom. Our classrooms are the first stop for the next generation of plant scientists, and we must engage...
Exploring the intersection between Chicago's eight-hour movement and Protestant religious culture over a fifty-year span, this project considers how workers and clergy contested the religious meaning of the eight-hour system...
This article presents seven points of focused dissonance between Jeremiah and Romans, by identifying how Romans 9–11 inverts the judgment language of Jeremiah 1–20 against Judah. Without claiming that the inversions in Romans...
In the intraoperative setting, the intersection of hand hygiene practices and contamination of the anesthesia workstation presents a critical juncture for reducing hospital acquired infections that ultimately lead to increased...
Background: The lack of palliative care (PC) services poses a significant risk for PC patients. Research indicates that patients' needs often go unmet when PC referral processes are not well established within a health system....
Macrophages serve as a first line of defense against microbial pathogens. Exposure to interferon-γ (IFNγ) increases interferon-stimulated gene (ISG) expression in these cells, resulting in enhanced antimicrobial and...
Introduction Delayed vasopressor initiation can occur with septic patients who arrive to the emergency department (ED) hemodynamically stable but decompensate later in their ED or hospital course. The relationship between...
Religion Matters: How Sociology Helps Us Understand Religion in Our World focuses on religion’s interplay with broader society, introducing students to the basic questions, ideas, and methods with which sociologists have...
Practitioners of course-based undergraduate research experiences (CUREs) often evaluate student learning through journal article style lab reports. In our biology department, CUREs are used in multiple required and elective...
In 1984, Ultrasound-Guided (USG) Intravenous (IV) access was first used to place central venous catheters (CVC) in real-time. This led to increased success rates, reduced procedural times, decreased site associated...
Community Health Needs Assessments and the developed strategies corresponding to any findings provide opportunities to improve the health of communities by targeted, coordinated efforts to meet the community needs. Thomas...
Background and Review of Literature: Postoperative nausea and vomiting (PONV) frequently occur in patients after anesthesia, significantly impacting patient satisfaction and potentially leading to untoward complications....
<b>Background and Review of Literature</b>: Caesarean sections are one of the most performed procedures in the operating room. Managing pain for these patients is vital to ensure a positive birthing experience for mothers and...
COVID-19 was primarily identified as a respiratory illness, but reports of patients presenting initially with cardiovascular complaints are rapidly emerging. Many patients also develop cardiovascular complications during and...
In his book, Music Education in an Age of Virtuality and Post-Truth, Woodford presents a welcomed discussion of the aims of music education in a time of political unrest. This timely text is needed due to the stresses of the...
Marfan syndrome (MFS) represents a genetic disorder with variable phenotypic expression. The main cardiovascular sequelae of MFS include aortic aneurysm/dissection and cardiomyopathy. While significant advances in the...
Coxiella burnetii is an obligate intracellular bacterium responsible for causing culture negative endocarditis. The manifestation of this condition several years following initial infection exhibits Coxiella’s ability to...
While new roles for the adult skeleton as an endocrine organ continue to emerge, our understanding of how bone homeostasis is maintained is also changing. Here we focus on BMP2, a molecule identified by its ability to induce...
Bradykinin, a local dermal kallikrein-kinin system product, increases skin blood flow via a cyclic GMP mechanism but is not the active cutaneous vasodilation molecule associated with cholinergic stimulation. However, the...
There is a need for anabolic therapies to treat degenerative bone
diseases. Mechanical loading stimulates anabolic and inhibits
catabolic pathways of bone leading to increased bone formation.
Osteocytes are the bone cell...
Obesity and metabolic dysfunction negatively impacts many tissues, including the skeleton. Calcium/calmodulin-dependent protein kinase kinase 2 (CaMKK2) is a serine/threonine protein kinase and key regulator of whole-body...
Head and neck squamous cell carcinomas (HNSCCs) have remained one of the common and lethal cancers around the world. HNSCC rapidly spread via the lymphatics system, leading to a higher percentage of initial late-stage diagnoses...
•Head and neck squamous cell carcinomas (HNSCCs) have remained one of the common and lethal cancers around the world. •HNSCC rapidly spread via the lymphatics system, leading to a higher percentage of initial late-stage...
Coxiella burnetii is an obligate intracellular bacterial pathogen and a causative agent of culture-negative endocarditis. While Coxiella initially infects alveolar macrophages, it may disseminate and cause endocarditis up to 20...
Why do neurocognitive disorders persist in people living with HIV while taking combination antiretroviral therapy
(cART)?
• The brain is a known reservoir for HIV.
• HIV can act on myeloid cell populations like...
Context: Lipid droplets (LDs) are cytoplasmic lipid storage organelles that have recently gained importance in host-pathogen interactions. They are surrounded by a phospholipid monolayer and store excess cellular free fatty...
Coxiella burnetii is an obligate intracellular bacterial pathogen and causative agent of Q fever. Chronic Q-fever manifests as potentially fatal endocarditis weeks to years after initial infection, suggesting Coxiella’s ability...
Osteoporosis is a silent, dangerous, pathology frequently undiagnosed until patients experience a major fracture. Fractures from osteoporosis lead to a 20% increase of mortality, revealing a need for novel anabolic therapies....
Peroxisome proliferator-activated receptors (PPARs) are important nuclear receptors in regulating macrophage lipid metabolism and modulating cellular inflammatory responses. In recent years, host cell PPARs have been linked to...
, and yl, y2, and y3
• We continue to learn more about the involvement of PPARs in
immune modulation.
Conclusion
• Further understanding PPARs upstream pathways and interactions can contextualize pathophysiology in...
Introduction: Bitter melon extract (BME) is known to inhibit breast cancer cells (MCF-7) proliferation. The PKC and ROK play critical roles in cell division, migration, and survival. However, the roles of protein kinase-c (PKC)...
Vibrio cholerae is a Gram-negative bacterium that is the cause of the diarrheal disease cholera. Many strains have developed antibiotic resistance which allows these mutated strains to elude traditional treatment. Among the...
Mental illness treatment in the United States has developed and changed drastically in the past century. Where in the early 1900s,one with a severe mental illness would be institutionalized, today, the same person could be...
Voltage sensitive calcium channels (VSCCs) are key components in coordinating extracellular signaling that influence calcium (Ca2+) influx and subsequent downstream signaling in a variety of tissues including bone. Previous...
The article demonstrates a need and placement of Roman Catholic pastoral theology and serves to offer important revelations about the state of pastoral theology in the Catholic tradition. The overarching goal of this article is...
A selection of sources for the cultural and political context of the early Roman Empire and the New Testament writings, this book includes public speeches, official inscriptions, annals, essays, poems, and documents of veiled...
Raised just outside Cincinnati, in the rural community of Rossmoyne, Ohio, Aaron Belford Thompson, Priscilla Jane Thompson, and Clara Ann Thompson wrote poetry that addressed Black American life in the early twentieth century....
Cryptococcus neoformans (Cn) is a pathogenic yeast that is the leading cause of fungal meningitis in immunocompromised patients. Various Cn virulence factors, such as the enzyme laccase and its product melanin, phospholipase,...
Clostridium difficile infection is particularly common in SOT patients and the consequences are severe. Fecal microbiota transplantation is an emerging, highly efficacious therapeutic modality for CDI but data on FMT success in...
Background: Recent studies indicated that chronic Salmonella infection contributes to increased risk of human colon cancer. In our previous studies, we found that Salmonella type III secretion effector protein AvrA can induce...
This novel is a semi-autobiographical work of fiction by Sara Cornelius Allison, wife of Indianapolis businessman and co-founder of the Indianapolis Motor Speedway James Allison. The work details the tumultuous relationship of...
To recognize and celebrate faculty efforts and excellence in teaching, faculty will showcase the innovative and interesting assignments, activities, and/or approaches they are using in their classrooms. in six different...
Instructional leadership can be conceptualized as the leadership approach wherein the school leader collaborates with teachers, to provide both support and guidance to establish the best teaching practices for students...
The work of children is school; despite this, medical providers and educators often live completely separately in their child-family interactions from one another. Yet, medical issues impact school success and school issues are...
The scientific process is nonlinear, unpredictable, and ongoing. Assessing the nature of science is difficult with methods that rely on Likert-scale or multiple-choice questions. This study evaluated conceptions about the...
Highlighting a teaching collaboration between Nursing and Library. Using health/research cases, this team classroom activity and “lightning presentation” allows students to engage and appraise unfamiliar research papers, using...
Multiple human malignancies rely on C-X-C motif chemokine receptor type 4 (CXCR4) and its ligand, SDF-1/CXCL12 (stroma cell-derived factor 1/C-X-C motif chemokine 12), to metastasize. CXCR4 inhibitors promote the mobilization...
A five minute "lightning talk" for an application to correlate LC Classification Outline classes with their respective call numbers, with the goal of the project make Library of Congress call numbers more...
BACKGROUND: Medical school curricula strives to teach as much material as can be retained in a limited amount of time. A common "gold standard" resource used building curricula are medical objectives suggested by national...
BACKGROUND: Medical school curricula strives to teach as much material as can be retained in a limited amount of time. A common "gold standard" resource used building curricula are medical objectives suggested by national...
• The Coronavirus Disease 2019 (COVID-19) pandemic led to the swift development of multiple vaccines
• Common side effects of COVID-19 vaccination include lymphadenopathy and fever in healthy adults
• Fever and...
Ferric citrate (FC) is an approved therapy for chronic kidney disease (CKD) pa-
tients as a phosphate (Pi) binder for dialysis-dependent CKD, and for iron de-
ficiency anemia (IDA) in non-dialysis CKD. Elevated Pi and IDA...
SEMA3F is an antilymphangiogenic signaling molecule expressed in the proliferating basal layer of normal epithelium. In orthotopic models of head and neck squamous cell carcinoma, loss of SEMA3F or its receptors results in...
Angiogenesis, the formation of new blood vessels from preexisting vasculature, is essential for many physiological processes, and aberrant angiogenesis contributes to some of the most prevalent human diseases, including cancer....
The US Department of Labor cites that while the United States has over 4 million registered nurses, many of them are no longer practicing. This statistic existed pre-pandemic, yet, is augmented in this current pandemic climate....
Introduction: The adenine diet is widely used in animal models to produce a tubu-lointerstitial fibrosis and inflammation that mimics human CKD in many aspects. These include the biochemical manifestations hyperphosphatemia and...
Context: Vibrio cholerae is the causative agent of cholera, the epidemic diarrheal disease. The colonization and subsequent diarrheal symptoms are produced due to toxin coregulated pilus (TCP) and cholerae toxin (CT)...
Case Study:
Short Limbs, Earlier Diagnosis: Antenatal Presentation of Cornelia de Lange Syndrome.
30-year old female presented at 35 weeks gestation to Maternal-Fetal Medicine with intrauterine growth restriction (IUGR) •...
This was a case study on a patient with SLE who received a heart transplant. Patients with SLE are generally not considered to be ideal candidates for transplantation due to auto-immunity involving many organ systems....
The Coronavirus Disease 2019 (COVID-19) pandemic led to the swift development of multiple vaccinations. Vaccine side effects were well-documented in the healthy adult cohort and included fever and lymphadenopathy, however, side...
The Coronavirus Disease 2019 (COVID-19) pandemic led to the swift development of multiple vaccinations. Vaccine side effects were well-documented in the healthy adult cohort and included fever and lymphadenopathy, however, side...
Background and Review of Literature: The presurgical anesthesia machine check is a critical procedure that all anesthesia providers must be capable of performing. Failing to perform an anesthesia machine check increases...
Because of the benefits of preemptive living donor (LD) transplant, the desire for LD is rising. However, in the last decade, there has been no increase in LD in the U.S, possibility due to older donor candidate population...
How do can we make our research methods courses more impactful, inclusive, and integrated? How can we engage students more effectively in a course many dread? My answer is to transform our Historical Research Methods course...
Reductions in skeletal muscle mass and function are often reported in patients with cancer-associated weight loss and are associated with reduced quality of life, impaired treatment tolerance, and increased mortality. Although...