Eccrine sweating glands are divided into functional units: I) a bulbous secretory coil that generates precursor fluid, and 2) a reabsorptive duct that transports the fluid to the skin surface. The secretory coils reside in the...
• Traditional medical education typically consists of two years of didactic, lecture-based education {Years 1 and 2), as well as two years of clinical clerkships and patient interactions {Years 3 and 4)
Introduction: Kisspeptin together with its receptor, GPR54 (Kiss1 R), are known for their function as the principal regulators of the onset of mammalian puberty. Given the characteristic growth spurt and bone development that...
The history and use of virtual and augmented reality dates back to the early 19th Century, Charles Wheatstone an English scientist, and inventor discovered that the brain interrupts stereoscopic photos and paintings differently...
Traditional medical education has recently seen major changes due to the coronavirus (COVID-19) pandemic. New pedagogical methods, including augmented reality (AR} and virtual reality (VR), arc on the rise as alternatives to...
Multi-system disorders may be difficult to differentiate between,
especially as genetic causes are still being defined and in light
of phenotypic variability. We present a case of a teen with
multiple congenital defects for...
Acute cardiac injury is a common cardiovascular complication of Covid19 and little is currently known about the long term implications of the complications and manifestations. Vascular complications show a hypercoagulable state...
Head and neck squamous cell carcinomas (HNSCCs) have remained one of the common and lethal cancers around the world. HNSCC rapidly spread via the lymphatics system, leading to a higher percentage of initial late-stage diagnoses...
The COVID-19 pandemic has created a unique situation for medical education worldwide as traditional medical training is not compatible with social distancing guidelines. Curriculums, content delivery, and procedures across...
Previous studies indicate that common fibular, tibial, and radial skin sympathetic nerve activity (SSNA) increases with physical stress in an exercise intensity-dependent manner but abates during ischemia when class Ill & IV...
The unique conditions of microgravity and radiation exposure in space have a substantial impact on human tissue function, resulting in extreme bone loss. The goal of this project is to synthesize the current knowledge on bone...
The ability to communicate with patients effectively continues to be a major hindrance for physicians and physician offices. Coordinating care via conventional telecommunication, involving making calls to a healthcare facility...
Healthcare disparities among different racial and ethnic groups are prevalent across the United States and worldwide. Healthcare provision may differ among racial and ethnic minorities, socioeconomic statuses, and insurance...
Osteoporosis is a silent, dangerous pathology frequently undiagnosed until patients experience a major fracture. About 1 in 2 women and 1 in 4 men ages 50 and above will experience bone fractures due to osteoporosis. Fractures...
Over 1.25 million people reside in nursing facilities in the United States. Nursing facilities have reported 268,707 confirmed cases of COVID-19 and 61,765 COVID-19 deaths as of the week of November 2, 2020. Indiana was one of...
Reported cases of isolated fetal ascites determined to be idiopathic have been shown to carry a favorable prognosis with frequent spontaneous resolution in utero (1,2,3). These cases generally reported better fetal outcomes...
Rubella was first described in the 1750s but took until 1941 when Congenital Rubella Syndrome was characterized to become medically significant. Similarly, zika virus was discovered in 1947 but only made headlines in 2016 when...
Ambulances are a target for theft and reportings of ambulance thefts has been increasing in the past several years. There is a paucity of research in this area, as a PubMed search of the terms ambulance theft yields only one...
Malignant mesothelioma typically presents in patients with asbestos exposure, with respiratory symptoms caused by primary pleural involvement with associated pleural effusion. Instead, this patient presented with a rapidly...
Older adults (65+) are at an increased risk of contracting COVID-19 and have higher incidences of adverse events. Nursing home residents are particularly vulnerable due to congregate living and the need for personal care. CMS...
Bitter melon extract (BME) is known to inhibit breast cancer cells (MCF-7) proliferation. Due to the high metabolic rate of cancer cells, we hypothesized that low glucose levels are detrimental to cell survivability and that...
Antibiotic resistance is not only a major threat to public health, with more than
700,000 deaths per year, but also has serious economic impacts.1 Nosocomial-
acquired antibiotic-resistant infections have well-established...
The COVID-19 pandemic resulted in widespread mRNA vaccinations against SARS-CoV2. Side effects include fatigue, headache, myalgia,
fever, nausea, and lymphadenopathy, frequently experienced in younger recipients (16-55 years)...
Chemotherapeutic agents, such as vincristine, are well known
antineoplastic and cytotoxic drugs, affecting patients broadly during
treatment of cancer. Well known side effects, such as constipation
and neuropathic pain,...
Nursing Homes (NH) often struggle to provide
Palliative Care (PC) to their residents with Alzheimer’s
and other Related Dementias (ADRDs). As a result,
many NHs are searching for external PC consultants to
help facilitate...
Recent studies describe racial and socioeconomic
(SES) disparities with mechanical thrombectomy
(MT) for acute ischemic stroke (AIS). Our study
investigated whether such disparities are present at
our institution and...
Chlamydia trachomatis (Ct) is the most common bacterial sexually transmitted pathogen and is a significant threat to the reproductive health of women. With an estimated 2.8 million new infections domestically and 131 million...
Due to the availability of information on the internet, patients are well informed of the several types of hernia repair available to them. They are also increasingly made aware of the litigious environment surrounding...
Kisspeptin together with its receptor, GPR54 (Kiss1R), are known for their function as the principal regulators of the onset of mammalian puberty. Given the characteristic growth spurt and bone development that occurs during...
Klotho is a regulatory anti-aging protein that is significantly expressed
in the choroid plexus, plays an important role in regulating the immune
response in the CNS, and diminishes with age. Klotho deficiency is...
3D visualization software is a useful tool in
patient education because it allows patients to
put an image to what a physician is describing
to them. With an emphasis on education of
young athletes on the potential...
Multiple sclerosis (MS), one of the most
prevalent immune-mediated neurological
disorders, is a chronic demyelinating disease
of the central nervous system that affects both
white and grey matter (Avasarala et....
Children with acute lymphoblastic leukemia
(ALL) suffer a litany of therapy induced side
effects. Methotrexate is a common chemotherapy agent
administered for the treatment of ALL. Failure to clear methotrexate from the body...
Calcitriol is a vitamin critical in regulating calcium
homeostasis, maintenance of musculoskeletal
integrity, and both a commonly prescribed medication
and over the counter supplement.
• However, the incidence of vitamin D...
• Myroides spp. are non-motile, aerobic, gram-
negative bacilli that are traditionally
opportunistic pathogens1.
• P. stuartii is a urease-producing, gram-negative
bacillus2.
• Myroides infections have been reported
60...
Traditionally, the acute wrist radiograph series is comprised of
posteroanterior (PA), oblique, and lateral projections. There is controversy within the field of Orthopedics, however, over the value of the oblique view in...
In 1984, Ultrasound-Guided (USG) Intravenous (IV) access was first used to place central venous catheters (CVC) in real-time. This led to increased success rates, reduced procedural times, decreased site associated...
Background: A child’s pain is different from pain experienced as adults. Different emotional and psychological factors can affect the child’s pain comprehension and stimulate their response to pain. Procedural pain can have...
Background and Review of Literature: A surgical site infection after posterior instrumented spinal fusion can negatively affect the patient and increase healthcare costs. Spinal fusions are becoming increasingly common as a...
Background: Many patients seek the advise from their primary care providers (PCPs) to provide insight into alternative treatment options, however, little is known about the practices of primary care providers (PCPs) and the...
The United States Preventative Services Task Force (USPSTF) recommends initiating colorectal cancer screening for asymptomatic, average-risk individuals at age 45, which is a new update to the previous recommendation of age 50....
1.5 million reported traumatic brain injuries (TBI) per year with varying degrees of severity that inflict injury at the cellular level. The Choroid Plexus (CP) plays a significant role in brain homeostasis. The CP has also...
Menopause, an age-related loss of sex hormone production in women, is one of the most common causes of osteoporosis. Previous work has established that this loss of sex hormones, in particular estrogen, causes dramatic loss of...
The dramatic increase in the prevalence of antibiotic resistant (AR) genes
in numerous bacterial species has been a heavily discussed topic within
the scientific community. Antibiotic resistant bacteria pose a serious
threat...
Ticks have been widely studied for their importance in disease transmission. In
Pennsylvania, four different ticks (associated with human diseases) are commonly
encountered: (1) Dermacentor variabilis (Rocky Mountain Spotted...