30 cm from heart level; CVAR), venoarteriolar response plus a decrease in perfusion pressure (venous occlusion by proximal cuff inflation; CVAR with DPP), and ischemia (arterial occlusion by proximal cuff inflation) and sweat...
Osteoporosis, a disease of low bone mineral density, affects 10 million Americans and triggers significant health problems and considerable socioeconomic burdens. Current treatments for osteoporosis have significant...
Context: Though anatomy is a vital part of a medical student’s education, three-dimensional visualization often ends in the laboratory, months into a medical student’s journey to becoming a physician. Many physicians would...
The Activin and BMP signaling pathways exert reciprocal effects on myogenesis and skeletal muscle regeneration after injury. Signal transduction in both pathways is mediated by ligand- induced activation of transcriptional...
Osteoporosis is a disease characterized by low bone mineral density due to the rate of bone resorption exceeding that of bone formation. Substantial evidence indicates the Bone Morphogenetic Protein (BMP) pathway promotes bone...
Mechanical loading is critical for bone remodeling. Voltage sensitive calcium channels (VSCCs) influence bone development and responses to loading. The α<sub>2</sub>δ<sub>1</sub> VSCC subunit regulates osteocyte...
Insulin resistance is associated with a high cumulative risk of AD and reduced cerebral glucose metabolism. New data suggest that increased hexosamine biosynthesis pathway (HBP) activity induces insulin resistance in adipose...
Inspired by the knowledge that the most pressing and enduring societal challenges of today and tomorrow are global in nature and the fundamental belief that integrative global learning is the essential heartbeat of a meaningful...
The taste receptor type 1 (TAS1R) family of heterotrimeric G protein-coupled receptors participates in monitoring energy and nutrient status. TAS1R member 3 (TAS1R3) is a bi-functional protein that recognizes amino acids such...
Introduction: According to the Centers for Disease Control and prevention (CDC), ensuring student access to needed physical and mental health care improves attendance, behavior, and achievement in the classroom. Academic...