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1. Abnormal Trafficking of Endogenously Expressed BMPR2 Mutant Allelic Products in Patients with Heritable Pulmonary Arterial Hypertension

Correspondências de palavras-chave:: ... . Austin4, Mark de Caestecker1,5* 1 Department of Cell and Developmental Biology, Vanderbilt University ...

... Pulmonary Arterial Hypertension (PAH) only have a 50% 5year survival[1]. For this reason there was ...

... receptor complexes then activate the canonical SMAD 1/5/8 pathway, which in turn leads to the ...

... transcriptional regulation of target genes such as PLOS ONE | www.plosone.org 1 November 2013 | Volume 8 | Issue ...

... EDTA, 1% Triton X-100, 10% glycerol containing proteinase inhibitor cocktail and phosphatase inhibitor ...

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O Criador:: Frump, A.L., Hamid, R., de Caestecker, M., Austin, E.D., and Lowery, Jonathan W.
Descrição:: More than 200 heterozygous mutations in the type 2 BMP receptor gene, BMPR2, have been identified in patients with Heritable Pulmonary Arterial Hypertension (HPAH). More severe clinical outcomes occur in patients with BMPR2...
Tipo:: Article

2. ABT-510 is an effective chemopreventive agent in the mouse 4-nitroquinoline 1-oxide model of oral carcinogenesis.

Correspondências de palavras-chave:: ... Research ABT-510 Is an Effective Chemopreventive Agent in the Mouse 4-Nitroquinoline 1-Oxide Model of Oral ...

... Carcinogenesis Rifat Hasina,1 Leslie E. Martin,1 Kristen Kasza,2 Colleen L. Jones,1 Asif Jalil1 and Mark W ...

... with preventive strategies. Using the 4-nitroquinoline 1-oxide (4-NQO) mouse model, we sought to define ...

... year (1). Despite numerous advances in therapy, the long-term survival for these patients has remained ...

... progression in an animal model whose genome is most similar to humans (1922). Although the 4-nitroquinoline 1 ...

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O Criador:: Martin, Leslie E., Jones, Colleen L., Hasina, Rifat, Jalil, Asif, Lingen, Mark W., and Kasza, Kristen
Descrição:: Despite numerous advances, the 5-year survival rate for head and neck squamous cell cancer (HNSCC) has remained largely unchanged. This poor outcome is due to several variables, including the development of multiple primary...
Tipo:: Article

3. Accessibility of ethics education and the formation of Catholic healthcare providers

Correspondências de palavras-chave:
O Criador:: Purzycka, Anna
Descrição:: Specifically in the medical field, Catholic providers rarely receive extensive education regarding the applications of moral theology to their work. Those knowledgeable on the topic have often gone to great lengths to acquire...
Tipo:: Article

4. Addressing Motivations and Barriers to Research Involvement during Medical School among Osteopathic Medical Students in the United States

Correspondências de palavras-chave:: ... 1,2 , Sarah Zahl 5,6 , Michael Baumann 7 and Jonathan W. Lowery 1,2,8, * 1 2 3 4 5 6 7 8 * Citation ...

... experiences intentionally designed with (1) a strong likelihood of gaining a publication, (2) financial ...

... ://doi.org/10.3390/educsci12060407 https://www.mdpi.com/journal/education Educ. Sci. 2022, 12, 407 2 of 12 1 ...

... . Respondents ranked items using a Likert scale from 15 as follows: (1) definitely will not; (2) probably will ...

... -COM (Table 1). Of the 272 students that responded, 56 (20.6%) were from the Class of 2022, 84 (30.9 ...

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O Criador:: Zahl, Sarah, Hum, Julia M., Jackson, Krista L., Griffin, Nicole, Lowery, Jonathan W., Nick, Benjamin, Herber, Jake, Hamby, T., Baumann, Michael, and Ogunbekun, Oladipupo
Descrição:: Involvement in research is regarded as a high-impact educational practice, which, for medical professionals, is associated with sharpened critical thinking and life-long learning skills, greater appreciation for evidence-based...
Tipo:: Article

5. The Aging Athlete: Paradigm of Healthy Aging

Correspondências de palavras-chave:
O Criador:: Gries, Kevin and Trappe, SW
Descrição:: 50% improved maximal aerobic capacity (VO2max) and enhanced skeletal muscle health (size, function, as well as metabolic and communicative properties) compared to non-exercisers at a similar age. By taking a reductionist...
Tipo:: Article

6. Allele-specific RNA Interference in FOP Silencing the FOP Gene

Correspondências de palavras-chave:
O Criador:: Rosen, V. and Lowery, Jonathan W.
Tipo:: Article

7. The BMP Pathway and Its Inhibitors in the Skeleton

Correspondências de palavras-chave:
O Criador:: Lowery, Jonathan W. and Rosen, V.
Descrição:: Bone morphogenetic proteins (BMPs) constitute the largest subdivision of the transforming growth factor-? family of ligands. BMPs exhibit widespread utility and pleiotropic, context-dependent effects, and the strength and...
Tipo:: Article

8. BMP Signaling and Vascular Disease

Correspondências de palavras-chave:
O Criador:: de Caestecker, M. and Lowery, Jonathan W.
Tipo:: Article

9. BMP Signaling in Vascular Development and Disease.

Correspondências de palavras-chave:
O Criador:: Lowery, Jonathan W. and de Caestecker, M.
Descrição:: Genetic and functional studies indicate that common components of the bone morphogenetic protein (BMP) signaling pathway play critical roles in regulating vascular development in the embryo and in promoting vascular homeostasis...
Tipo:: Article

10. Bmp2 and Bmp4 Exert Opposing Effects in Hypoxic Pulmonary Hypertension

Correspondências de palavras-chave:
O Criador:: Jones, M.T., Frank, D.B., Mortlock, D.P., de Caestecker, M., Chandler, R.L., Anderson, L.A., and Lowery, Jonathan W.
Descrição:: The bone morphogenetic protein (BMP) type 2 receptor ligand, Bmp2, is upregulated in the peripheral pulmonary vasculature during hypoxia-induced pulmonary hypertension (PH). This contrasts with the expression of Bmp4, which is...
Tipo:: Article

1. Abnormal Trafficking of Endogenously Expressed BMPR2 Mutant Allelic Products in Patients with Heritable Pulmonary Arterial Hypertension

2. ABT-510 is an effective chemopreventive agent in the mouse 4-nitroquinoline 1-oxide model of oral carcinogenesis.

3. Accessibility of ethics education and the formation of Catholic healthcare providers

4. Addressing Motivations and Barriers to Research Involvement during Medical School among Osteopathic Medical Students in the United States

5. The Aging Athlete: Paradigm of Healthy Aging

6. Allele-specific RNA Interference in FOP Silencing the FOP Gene

7. The BMP Pathway and Its Inhibitors in the Skeleton

8. BMP Signaling and Vascular Disease

9. BMP Signaling in Vascular Development and Disease.

10. Bmp2 and Bmp4 Exert Opposing Effects in Hypoxic Pulmonary Hypertension

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1. Abnormal Trafficking of Endogenously Expressed BMPR2 Mutant Allelic Products in Patients with Heritable Pulmonary Arterial Hypertension

2. ABT-510 is an effective chemopreventive agent in the mouse 4-nitroquinoline 1-oxide model of oral carcinogenesis.

3. Accessibility of ethics education and the formation of Catholic healthcare providers

4. Addressing Motivations and Barriers to Research Involvement during Medical School among Osteopathic Medical Students in the United States

5. The Aging Athlete: Paradigm of Healthy Aging

6. Allele-specific RNA Interference in FOP Silencing the FOP Gene

7. The BMP Pathway and Its Inhibitors in the Skeleton

8. BMP Signaling and Vascular Disease

9. BMP Signaling in Vascular Development and Disease.

10. Bmp2 and Bmp4 Exert Opposing Effects in Hypoxic Pulmonary Hypertension

Filtre sua busca