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10/16/2009

Collezione

Submitted Manuscripts and Publications - College of Arts & Sciences

The lipidomes of C. elegans with mutations in asm-3/acid sphingomyelinase and hyl-2/ceramide synthase show distinct lipid profiles during aging

Corrispondenze di parole chiave:

... ). Interestingly, TAG increased in 10-day old animals compared to 1-day old animals in N2, daf-16, and hyl-2 ...

... hyl-2, asm-3, daf-16, and eat-2 backgrounds to that of wildtype 10-day animals (Figure 4C4F ...

... daf-16 to N2. Both 10-day old hyl-2 and daf16 showed increases in LPCs compared to 10-day wildtype ...

... analyzed total PUFAs, we found that both hyl-2 and daf-16 mutants had higher amounts of PUFAs than 10-day ...

... animals. (F) Comparison of 10-day old daf-16 animals versus 10-day old N2 animals. www.aging-us.com 656 ...

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Creatore:

Staab, Trisha, McIntyre, Grace, Bromley, S., Raftery, D., Chan, Jason, Wang, L., Radeny, J., Bettcher, L., Guillen, Melissa, Peck, M. , and Kalil, A.

Descrizione:

Lipid metabolism affects cell and physiological functions that mediate animal healthspan and lifespan. Lipidomics approaches in model organisms have allowed us to better understand changes in lipid composition related to age...

Tipo di risorsa:

Research Paper