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3/1/2012

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Submitted Manuscripts and Publications - College of Arts & Sciences

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California Institute of Technology

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  • The impact of C. elegans ceramide glucosyltransferase enzymes on the beneficial effects of B. subtilis lifespan

    Keyword matches:
    ... beneficial effects of B. subtilis lifespan Chelsey L Arvin 1, Zachary Sibila 2, Regina Lamendella 3, Jason ...
    ... phenotype of B. subtilis. However, cgt-1(ok1045) and cgt-3(tm504) did play a minor role in blocking stress ...
    ... mutants (cgt-1(tm1027), cgt-1(ok1045), cgt-2(tm1192), cgt-3(tm504)) fed on E. coli (OP50; yellow) or B ...
    ... genes (cgt-1, cgt-2, and cgt-3) that are thought to have CGT enzymatic activity in C. elegans. Previous ...
    ... studies suggest that cgt-1 and cgt-3 have a greater number of amino acids relating to functional enzymatic ...

    Creator:

    Arvin, Chelsey L., Sibila, Zachary, Lamendella, R., Chan, Jason, and Staab, Trisha

    Description:

    Ceramide glucosyltransferase (CGT) adds sugar moieties to ceramide, forming glucosylceramides that play roles in immune signaling, stress response, and host-bacterial interactions. Here, we examined whether mutations in cgt...

    Type:

    Article