The spread of antibiotic resistance among bacteria is a potential threat to the effectiveness of antibiotics currently used for controlling common human pathogens. Also, the resistance to current antibiotics is spreading at a...
Previous studies indicate that common fibular, tibial, and radial skin sympathetic nerve activity (SSNA) increases with physical stress in an exercise intensity-dependent manner but abates during ischemia when class Ill & IV...
CONTEXT. Prior research has shown that nursing home residents have a significant burden of symptoms including pain, nervous and depressed feelings, fatigue, and lack of energy. OPTIMISTIC is an 8-year initiative funded by the...
Chlamydia trachomatis (Ct) is the most common bacterial sexually transmitted pathogen and is a significant threat to the reproductive health of women. With an estimated 2.8 million new infections domestically and 131 million...
The DNA dependent protein kinase (DNA-PK) is a validated target for cancer therapeutics that drives the DNA damage response (DDR) and plays a critical role as a primary sensor in the non-homologous end joining (NHEJ) DNA double...
Purpose: Partial nephrectomies by their nature are associated with renal volume loss. Our goal from this study is to examine renal volume loss over time post partial nephrectomy.
Material and Methods: Fifty patients were...
Palladium is often used in the synthesis of Active Pharmaceutical Ingredients (APIs), although it is toxic to ingest. As it is difficult to remove, it is imperative to develop optimal palladium sensors that can be utilized in...
2 fold, either as a vector-expressed shRNA or as a transfected siRNA. We randomly mutagenized gFA2 to create a gFA2 variant sub-library. We screened this sub-library in primary FA fibroblasts and identified two gFA2 variants,...
Calcitriol is a vitamin critical in regulating calcium
homeostasis, maintenance of musculoskeletal
integrity, and both a commonly prescribed medication
and over the counter supplement.
• However, the incidence of vitamin D...
Traditionally, the acute wrist radiograph series is comprised of
posteroanterior (PA), oblique, and lateral projections. There is controversy within the field of Orthopedics, however, over the value of the oblique view in...
INTRODUCTION: Two out of five U.S. citizens born after 2014 are expected to develop type 2 diabetes (T2D). T2D patients are at increased risk for fracture and impaired fracture healing, including: increased frequency of partial...
The great saphenous vein (GSV) should be considered as a vascular access point in cases of difficult access such as in trauma patients or hypovolemic patients. The GSV has been proven to be a viable vessel for peripheral venous...
Ticks have been widely studied for their importance in disease transmission. In
Pennsylvania, four different ticks (associated with human diseases) are commonly
encountered: (1) Dermacentor variabilis (Rocky Mountain Spotted...
Context: Indwelling Urinary Catheterization (IUC) is among the most common procedures performed in the inpatient setting. Because there are risks associated with IUC, efforts to reduce its use when unnecessary should be made....
Introduction: 23andMe provides consumers the opportunity to receive genetic information without involvement of a healthcare provider. As 23andMe continues to increase the number of variants and genetic diseases included in...
Nursing Homes (NH) often struggle to provide
Palliative Care (PC) to their residents with Alzheimer’s
and other Related Dementias (ADRDs). As a result,
many NHs are searching for external PC consultants to
help facilitate...
A comprehensive yet efficient evaluation of living kidney donor volunteers (LKDV) is key to a successful transplant program. Donor selection is complex and must balance donor medical suitability, compatibility issues and donor...
Correlations exist between undergraduate GPA,
MCAT, and COMLEX-USA Level 1 scores as well as
between course grades and overall COMLEX score
(Wong et al. 2009 & Sefcik et al. 2003).
• Longitudinal reports on ProgressIQ...
Paraspinal inhibition is an osteopathic manipulative treatment (OMT) purported to work via the sympathetic nervous system and aid in restoring autonomic homeostasis. Despite clinical anecdotal evidence, the mechanism of action...