In the United States, one of the biggest issues that every state is experiencing is the shortage in doctors. Primary Care Physicians make up a huge percentage of the shortage in doctors. The Midwest took a huge hit by this...
Children with acute lymphoblastic leukemia
(ALL) suffer a litany of therapy induced side
effects. Methotrexate is a common chemotherapy agent
administered for the treatment of ALL. Failure to clear methotrexate from the body...
Healthcare disparities among different racial and ethnic groups are prevalent across the United States and worldwide. Healthcare provision may differ among racial and ethnic minorities, socioeconomic statuses, and insurance...
Recent studies describe racial and socioeconomic
(SES) disparities with mechanical thrombectomy
(MT) for acute ischemic stroke (AIS). Our study
investigated whether such disparities are present at
our institution and...
Over 1.25 million people reside in nursing facilities in the United States. Nursing facilities have reported 268,707 confirmed cases of COVID-19 and 61,765 COVID-19 deaths as of the week of November 2, 2020. Indiana was one of...
There is a need for anabolic therapies to treat degenerative bone
diseases. Mechanical loading stimulates anabolic and inhibits
catabolic pathways of bone leading to increased bone formation.
Osteocytes are the bone cell...
Obesity and metabolic dysfunction negatively impacts many tissues, including the skeleton. Calcium/calmodulin-dependent protein kinase kinase 2 (CaMKK2) is a serine/threonine protein kinase and key regulator of whole-body...
Head and neck squamous cell carcinomas (HNSCCs) have remained one of the common and lethal cancers around the world. HNSCC rapidly spread via the lymphatics system, leading to a higher percentage of initial late-stage diagnoses...
Why do neurocognitive disorders persist in people living with HIV while taking combination antiretroviral therapy
(cART)?
• The brain is a known reservoir for HIV.
• HIV can act on myeloid cell populations like...