Hart, C, Gries, Kevin, Ryan, Z, Kunz, H, Laurenti, M, Polley, E, Zhang, X, Dalla Man, C, Moore, N, Lanza, I, Vella, A, Parvizi, M, and Jensen, M

Obesity is accompanied by numerous systemic and tissue-specific derangements, including systemic inflammation, insulin resistance, and mitochondrial abnormalities in skeletal muscle. Despite growing recognition that adipose...

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Gries, Kevin and Trappe, SW

50% improved maximal aerobic capacity (VO2max) and enhanced skeletal muscle health (size, function, as well as metabolic and communicative properties) compared to non-exercisers at a similar age. By taking a reductionist...

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Mikelis, C., Zheng, Y., Zahra, F., Gutkind, J., Zabet-Moghaddam, M., Akwii, R., Doci, Colleen L., Tullar, P., and Sajib, S.

Lymphangiogenesis is an essential physiological process but also a determining factor in vascular-related pathological conditions. Angiopoietin-2 (Ang2) plays an important role in lymphatic vascular development and function and...

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Gries, Kevin, Zhang, X., Polley, E.C. , Hart, C.R. , Kunz, H.E. , and Lanza, I.R.

Declining fitness (˙VO2 peak) is a hallmark of ageing and believed to arise from decreased oxygen delivery and reduced muscle oxidative capacity. Physical activity is a modifiable lifestyle factor that is critical when...

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