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Bone Morphogenetic Protein 2

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Faculty Publications and Research - MUCOM

1. Bmp2 and Bmp4 Exert Opposing Effects in Hypoxic Pulmonary Hypertension

Keyword matches:
Creator:: Jones, M.T., Frank, D.B., Mortlock, D.P., de Caestecker, M., Chandler, R.L., Anderson, L.A., and Lowery, Jonathan W.
Description:: The bone morphogenetic protein (BMP) type 2 receptor ligand, Bmp2, is upregulated in the peripheral pulmonary vasculature during hypoxia-induced pulmonary hypertension (PH). This contrasts with the expression of Bmp4, which is...
Type:: Article

2. Periosteal BMP2 Activity Drives Bone Graft Healing.

Keyword matches:
Creator:: Cox, K., Gamer, L., Bosshardt, D., Rosen, V., Lowery, Jonathan W., and Chappuis, V.
Description:: Bone graft incorporation depends on the orchestrated activation of numerous growth factors and cytokines in both the host and the graft. Prominent in this signaling cascade is BMP2. Although BMP2 is dispensable for bone...
Type:: Article

3. The Role of BMP2 Signaling in the Skeleton.

Keyword matches:
Creator:: Capelo, L.P., Chappuis, V., Kokabu, S, Lowery, Jonathan W., Rosen, V., Pazin, D., and Intini, G.
Description:: While new roles for the adult skeleton as an endocrine organ continue to emerge, our understanding of how bone homeostasis is maintained is also changing. Here we focus on BMP2, a molecule identified by its ability to induce...
Type:: Article