Kidney transplantation is a major surgical intervention and patients undergoing counseling for this procedure do not always fully understand the essentials of this procedure. We present an improved way to facilitate patient...
The goal of this project is to build a teaching tool geared towards patients, students, and clinicians to further educate themselves about the anatomical and biochemical implications of various syndromes involving depression...
Context 3-Dimensional (3D) imaging is utilized in a variety of ways in medicine, including ultra-sound facial scanning in utero, breast cancer detection, and mapping blood vessels. 3D imaging can also be used to educate both...
3D visualization research is useful as a learning tool for medical students learning human anatomy and as a diagnostic tool for practicing physicians. Here we explore the use of this application of medical imaging in...
Introduction. Multiple myeloma (MM) is a hematological cancer characterized by the expansion and accumulation of monoclonal malignant plasma cells in the bone marrow (BM). Interactions between MM cells and cells of the bone/BM...
A positive association between beta-carotene (BC)-rich food intake and a reduction in metabolic disorder incidence, including heart disease, is prevalent in humans. Similarly, preclinical research finds dietary BC...
Osteocyte (Ot)-derived Sclerostin (Scl) has local actions in bone mediated by Lrp 4/5/6 receptors, inhibiting bone formation and stimulating bone resorption by antagonizing Wnt signaling. Emerging evidence suggests that Scl...
This project created the first website capable of searching published biomedical knowledge and returning a rank ordered list of actions most effective at improving health. These actions have font scaled based on the odds ratios...
Introduction: The Catholic medical ethic is supported by a rich intellectual tradition and remains foundational to the practice of medicine, especially within Catholic hospitals. In the US, the United States Conference of...
Head and Neck Squamous Cell Carcinoma (HNSCC) is one of the most common cancers in the world, and even in developed countries like the United States, the five-year survival is only 65%. This already low survival rate drops...
Troglitazone (TRO), a peroxisome proliferator-activated receptor (PPAR) agonist, was a drug used as an anti-inflammatory and anti-diabetic agent. We had previously investigated a PPAR agonist that induced apoptosis in dose...
Mobile Integrated Healthcare (MIH), also called Community Paramedicine (CP) or EMS 3.0, is a novel approach to prehospital care. With the use of specially trained paramedics, MIH-CP seeks to fill the current healthcare gaps in...
This project, OPTIMISTIC, is a retrospective study that focuses on Congestive Heart Failure(CHF) in Indiana Nursing homes. The purpose of the study was to find better ways in which to implement in house care to these CHF...
Introduction: OPTIMISTIC is a project funded by the Centers for Medicaid and Medicare Services (CMS) that is aimed, in part, at the reduction of unnecessary hospitalization of nursing facility residents. Data from the initial...
Coxiella burnetii is an obligate intracellular Gram-negative bacterium that causes Q fever in humans. While acute infection manifests as self-limiting flu-like illness, chronic Q fever presents as non-culturable endocarditis,...
Introduction: Externally added survival/growth factors are essential for the survival of healthy cells, however cancer cells are believed to be self-sufficient in supporting their auto-proliferation without the need of...
Chronic Kidney Disease (CKD) affects approximately 1 in 10 Americans. Diabetic nephropathy is also associated with the development of chronic kidney disease-mineral bone disorder (CKD-MBD). CKD-MBD disrupts the normal...
Postpartum preeclampsia refers to hypertension and proteinuria after delivery, and the occurrence of a seizure within six weeks after delivery is called postpartum eclampsia. Etiology is unknown but theorized to involve...
Context: Skeletal muscle is essential for proper bodily functions by playing key roles in strength and movement, and it accounts for roughly 50% of our total body mass. Decreases in total muscle mass or mass-specific function...
There are limited data regarding the research experience and/or interest among osteopathic medical students despite a rapidly increasing enrollment and expansion of the number of osteopathic medical schools. A 2016 study of...