Many Gram negative bacteria including Salmonella enterica species exhibit evolving multi-drug resistance coded for on their chromosome and on mobile genetic elements. Salmonella species carrying multi-drug resistance plasmids...
Cold-induced vasodilation (CIVD) is a phenomenon involving a counterintuitive increase in skin blood flow during cold exposure. Although CIVD was first described in 1930, CIVD mechanisms remain unknown. CIVD research has...
Osteoporosis is a disease of low bone mineral density that affects 10 million Americans and accounts for 1.5 million fractures annually. With an additional 34 million Americans at risk for developing the disease, osteoporosis...
The taste receptor type 1 (TAS1R) family of heterotrimeric G protein-coupled receptors participates in monitoring energy and nutrient status. TAS1R member 3 (TAS1R3) is a bi-functional protein that recognizes amino acids such...
Marfan syndrome (MFS) represents a genetic disorder with ranging clinical presentation, most notably ascending aortic aneurysms. There has been extensive research to elucidate the mechanistic biochemistry of this disease. In...
Clostridium difficile infection is particularly common in SOT patients and the consequences are severe. Fecal microbiota transplantation is an emerging, highly efficacious therapeutic modality for CDI but data on FMT success in...
Vibrio cholerae colonization of the host requires stringent response activation of TCP, the Toxin-Coregulated Pilus Cholera is an epidemic diarrheal disease caused by the Gramnegative bacterium Vibrio cholerae. In order to...
In conjunction with recent curricular changes at US medical schools, histology instruction has undergone significant changes. One major change has been the steady shift from traditional microscopy laboratory sessions to the...