Friedreich ataxia (FRDA) is an autosomal recessive neuro- and cardio-degenerative disorder caused by decreased expression of frataxin, a protein that localizes to mitochondria and is critical for iron-sulfur-cluster (ISC)...
Numerous surgical approaches have been proposed to treat aortic arch hypoplasia (Figures 1&2). These repairs can vary based upon patient age (i.e. neonatal vs larger child), and therefore the mobility of the aorta. Most repairs...