Osteoporosis, a disease of low bone density that occurs when bone resorption ex-ceeds bone formation, places individuals at a higher risk for fracture and disability. We previously reported that deletion of the Bmpr2 gene in...
Current therapies for low bone mass consist of inhibiting osteoclast activity or increasing the PTH or Wnt signaling pathways. These approaches have significant drawbacks that limit their use in specific patient populations...