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Abstract

Correspondências de palavras-chave:
O Criador:: Hum, Julia
Descrição:: Fibroblast growth factor-23 (FGF23) controls key responses to systemic phosphate increases through its phosphaturic actions on the kidney. In addition to stimulation by phosphate, FGF23 positively responds to iron deficiency...
Tipo:: poster

Bringing Attention to Lesser-known Bone Remodeling Pathways

Correspondências de palavras-chave:
O Criador:: Donnelly, Stephen OMS-4, Bender, Cecelia OMS-2, Jackson, Krista OMS-1, Guan, Henry OMS-4, Hum, Julia, Shadmand, Mehdi OMS-2, Tobin, Kirby OMS-2, Yates, Sydni OMS-2, and Lowery, Jonathan W.
Descrição:: Osteoporosis, a disease of low bone mass, places individuals at enhanced risk for fracture, disability, and death. In the USA, hospitalizations for osteoporotic fractures exceed those for heart attack, stroke, and breast cancer...
Tipo:: Article

Developing an in vitro model of CKD-MBD induced αKlotho suppression

Correspondências de palavras-chave:
O Criador:: Tobin, Kirby, Hum, Julia, Oberhelman, Forrest, LaFave, Nicole, Young, Collin, and Waite, Timothy
Descrição:: Chronic Kidney Disease (CKD) affects approximately 1 in 10 Americans. Diabetic nephropathy is also associated with the development of chronic kidney disease-mineral bone disorder (CKD-MBD). CKD-MBD disrupts the normal...
Tipo:: poster

Developing an In Vitro Model of CKD-MBD Induced αKlotho Suppression

Correspondências de palavras-chave:: ... qPCR experiments 2.5 2 Repeat experiment in HK-2 (proximal tubule) cell line 1.5 1 0.5 BACKGROUND ...

... of fluid stress and a pattern of decreased gene expression after 1 hour RESULTS Densitometry Units ...

... Chronic Kidney Disease (CKD) affects approximately 1 in 10 Americans. Diabetic nephropathy is also ...

... of CKD-MBD. SUMMARY & CONCLUSIONS 0 Static 15 min OFSS 30 min OFSS Figure 1. A) HEK cells were ...

... Approximately 1:10 Americans have CKD-MBD CKD-MBD disrupts the normal bone-kidney endocrine axis and ...

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O Criador:: Tobin, Kirby, Hum, Julia, Oberhelman, Forrest, and Waite, Timothy
Descrição:: Chronic Kidney Disease (CKD) affects approximately 1 in 10 Americans. Diabetic nephropathy is also associated with the development of chronic kidney disease-mineral bone disorder (CKD-MBD). CKD-MBD disrupts the normal...
Tipo:: poster

Identification of Commercially Available Antibodies That Block Ligand-Binding by BMPR2

Correspondências de palavras-chave:
O Criador:: Gorrell, Ruthann, Yates, Sydni, Hudnall, Aaron, Hum, Julia, Geyman, Logan, Lawless, Warren, Totten, Madeline, Newby, Jordan, Lowery, Jonathan, and Schoerning, Laura
Descrição:: The Bone Morphogenetic Protein (BMP) signaling pathway comprises the largest subdivision of the Transforming Growth Factor (TGFβ) superfamily. BMP signaling plays essential roles in both embryonic development and postnatal...
Tipo:: poster

Mechanical stimulation in vitro regulates pro-inflammatory cytokines: potential insight into soft tissue manual therapies for osteopenia and sarcopenia

Correspondências de palavras-chave:: ... tissue manual therapies for osteopenia and sarcopen1a Arie Anloague 1, 2, Aaron Mahoney 1, 2, Oladipupo ...

... Ogunbekun 1, 2, Taylor A. Hiland 1, 2, William R. Thompson 1, 3A, Bryan Larsen1, M. Terry Loghmani 1, 3A ...

... , Julia M. Hum 1, 2 and Jonathan W. Lowery 1, 2, 3 * 1 Division of Biomedical Science, Marian University ...

... any significant findings in the MC3T3E 1 line, it gave us key insight into our next steps for the ...

... and a decrease in CTx- 1, a marker for bone resorption. One of these insights has led us to begin ...

mais >>
O Criador:: Larsen, Bryan, Ogunbekun, Oladipupo, Loghmani, M. Terry, Thompson, William, Hum, Julia, Hiland, Taylor, Lowery, Jonathan, Mahoney, Aaron, and Anloague, Aric
Descrição:: Objecti ve: Soft tissue manual therapies are commonly utilized by osteopathic physicians, chiropractors, physical therapists and massage therapists. These techniques are predicated on subjecting tissues to biophysical...
Tipo:: Poster

Mechanical stimulation of soft tissue cells regulates osteoblast differentiation and activity through soluble factors

Correspondências de palavras-chave:: ... other serious diseases among postmenopausal women in the United States. Mayo Clin Proc, 2015. 90(1): p ...

... (IL)-1-alpha, IL-6, IL-8 and CXCL5) known to restrict the differentiation and/or activity of bone ...

... marker N-terminal propeptide of type 1 procollagen and decreased serum levels of the bone resorption ...

... marker collagen type 1 C-telopeptide in young, healthy women and increased serum P1NP levels in some ...

... : potential insight into soft tissue manual therapies. BMC Res Notes, 2020. 13(1): p. 400. Raisz, L.G ...

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O Criador:: Hum, Julia, Hiland, Taylor, Anloague, Aric , Melchior, Ross, Lowery, Jonathan, and Delgado-Calle, Jesus
Descrição:: Osteoporosis is a disease of low bone mass that places individuals at enhanced risk for fracture, disability, and death. Hospitalizations for osteoporotic fractures exceeds those for heart attack, stroke, and breast cancer...
Tipo:: Poster

Mice Lacking the a2d1 Auxiliary Voltage Sensitive Calcium Channel Subunit Have Impaired Bone Quantity and Decreased Lean Mass

Correspondências de palavras-chave:
O Criador:: Farach-Carson Mary, Sharma, Karan, Kelly, Madison, Hum, Julia, Noonan, Megan, Yi, Xin, and Robling, Alexander
Descrição:: Mechanical loading is critical for bone remodeling. Voltage sensitive calcium channels (VSCCs) influence bone development and responses to loading. The α₂δ₁ VSCC subunit regulates osteocyte...
Tipo:: poster

Notum: A Novel Regulator of Bone and Its Implications in Osteoporosis

Correspondências de palavras-chave:: ... hour Figure 1. A) Cells from an osteocyte cell line, MLOY4, were cultured, harvested and subjected to ...

... decreases Notum protein expression in an osteocyte cell line, MLOY4. 1 hour B) 0.5 SUMMARY Static A) 1 ...

... Western blot. Embryo. (embryonic) sample age: embryonic week 12. Young samples: 1 week, 4 weeks, 8 weeks ...

... , development, and healing. HYPOTHESIS Notum B-actin About 1 in 2 women and 1 in 4 men ages 50 and above will ...

... orbital shear stress for 15 minutes, 30 minutes, 1 hour, and 2 hours. Protein was then isolated and ...

mais >>
O Criador:: Castanon, Mariah, Hum, Julia, Marshall, Vince, and Wacker, Bryan
Tipo:: poster

Notum: A Novel Regulator of Bone and Its Implications in Osteoporosis

Correspondências de palavras-chave:: ... patients experience a major fracture. B-adin B) J., About 1 in 2 women and 1 in 4 men ages 50 and above ...

... .~ (embl'yonic) sample age: embryonic week 12. "Young samples 1 week, 4 weeks, 8 weeks. 'Old~ samples: 15 weeks ...

... Aging increases the expression of the Notum gene in a mouse model. ~ ~ 15min - - - 1 hour 30min. ' . 8 ...

... ) Figure 1. A) Cth from an 01:teocyte eel line, MLOY4, were cultured, harvesled and subjected lo mechanical ...

... loading mimicked via orbital shelr stre" for 15 minutes, 30 minu1es. 1 t.our, and 2 hours. Pro1ein was ...

mais >>
O Criador:: Castanon, Mariah, Hum, Julia, Wacker, Bryan, and Marshall, Vince
Descrição:: Osteoporosis is a silent, dangerous pathology frequently undiagnosed until patients experience a major fracture. About 1 in 2 women and 1 in 4 men ages 50 and above will experience bone fractures due to osteoporosis. Fractures...
Tipo:: Poster

Abstract

Bringing Attention to Lesser-known Bone Remodeling Pathways

Developing an in vitro model of CKD-MBD induced αKlotho suppression

Developing an In Vitro Model of CKD-MBD Induced αKlotho Suppression

Identification of Commercially Available Antibodies That Block Ligand-Binding by BMPR2

Mechanical stimulation in vitro regulates pro-inflammatory cytokines: potential insight into soft tissue manual therapies for osteopenia and sarcopenia

Mechanical stimulation of soft tissue cells regulates osteoblast differentiation and activity through soluble factors

Mice Lacking the a2d1 Auxiliary Voltage Sensitive Calcium Channel Subunit Have Impaired Bone Quantity and Decreased Lean Mass

Notum: A Novel Regulator of Bone and Its Implications in Osteoporosis

Notum: A Novel Regulator of Bone and Its Implications in Osteoporosis

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