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Filtrage par: Créateur Doci, Colleen L. La langue English Éditeur Nature Publishing Group

Endothelial RhoA GTPase is essential for in vitro endothelial functions but dispensable for physiological in vivo angiogenesis.

Créateur:

Gutkind, J. Silvio, Kubota, Yoshiaki, Akwii, Racheal Grace, Minchew, Shelby A., Cobos, Christopher, Ichiyama, Yusuke, Zheng, Yi, Tuz Zahra, Fatema, Sajib, Sanaullah, Tullar, Paul E., Doci, Colleen L., and Mikelis, Constantinos M.

La description:

Imbalanced angiogenesis is a characteristic of several diseases. Rho GTPases regulate multiple cellular processes, such as cytoskeletal rearrangement, cell movement, microtubule dynamics, signal transduction and gene...

Type:

Article
The novel tumor suppressor NOL7 post-transcriptionally regulates thrombospondin-1 expression.

Créateur:

Zhou, G., Doci, Colleen L., and Lingen, M.W.

La description:

Thrombospondin-1 (TSP-1) is an endogenous inhibitor of angiogenesis whose expression suppresses tumor growth in vivo. Like many angiogenesis-related genes, TSP-1 expression is tightly controlled by various mechanisms, but there...

Type:

Article
Semaphorin signaling in angiogenesis, lymphangiogenesis and cancer.

Créateur:

Gutkind, J. Silvio, Doci, Colleen L., and Sakurai, Atsuko

La description:

Angiogenesis, the formation of new blood vessels from preexisting vasculature, is essential for many physiological processes, and aberrant angiogenesis contributes to some of the most prevalent human diseases, including cancer....

Type:

Article