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Correspondências de palavras-chave:
O Criador:: Wang, Lou, Staab, Trisha, Radeny, J, McIntyre, Grace, and Chan, Jason
Descrição:: The increase in our aging population in combination with the growing incidence of late-life conditions presents a need for research on healthy aging. Here, we present work examining the roles of sphingolipid metabolism on...
Tipo:: Conference Proceeding

Correspondências de palavras-chave:: ... beneficial effects of B. subtilis lifespan Chelsey L Arvin 1, Zachary Sibila 2, Regina Lamendella 3, Jason ...

... block the beneficial effects of Bacillus subtilis on C. elegans lifespan. We found that loss of cgt-1 or ...

... phenotype of B. subtilis. However, cgt-1(ok1045) and cgt-3(tm504) did play a minor role in blocking stress ...

... of glucosylceramides in host-bacterial interaction. 4/5/2023 - Open Access Figure 1. Loss of CGT ...

... mutants (cgt-1(tm1027), cgt-1(ok1045), cgt-2(tm1192), cgt-3(tm504)) fed on E. coli (OP50; yellow) or B ...

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O Criador:: Arvin, Chelsey L., Sibila, Zachary, Lamendella, R., Chan, Jason, and Staab, Trisha
Descrição:: Ceramide glucosyltransferase (CGT) adds sugar moieties to ceramide, forming glucosylceramides that play roles in immune signaling, stress response, and host-bacterial interactions. Here, we examined whether mutations in cgt...
Tipo:: Article

Correspondências de palavras-chave:: ... , Margaret P. Peck4, Azia P. Kalil4, Samantha P. Bromley4, Daniel Raftery3, Jason P. Chan1 1 Department of ...

... Received: June 24, 2022 Accepted: February 1, 2023 Published: February 13, 2023 Copyright: 2023 Staab et ...

... analyzed longitudinal lipid changes in wild type animals compared to mutants at 1-, 5-, and 10-days of age ...

... animals exhibit increased triacylglycerols (TAG) at 10-days compared to 1-day, and decreased ...

... determinants of lifespan and disease conditions [1, 2]. For example, lipid classes including www.aging-us.com ...

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O Criador:: Staab, Trisha, McIntyre, Grace, Bromley, S., Raftery, D., Chan, Jason, Wang, L., Radeny, J., Bettcher, L., Guillen, Melissa, Peck, M. , and Kalil, A.
Descrição:: Lipid metabolism affects cell and physiological functions that mediate animal healthspan and lifespan. Lipidomics approaches in model organisms have allowed us to better understand changes in lipid composition related to age...
Tipo:: Research Paper

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