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Filtering by: Creator Arbor, Sage Collection Faculty Publications and Research - MUCOM

Amyloid-beta Alzheimer targets - protein processing, lipid rafts, and amyloid-beta pores.

Creator:

Arbor, Sage, Medhane, Cumbay, and LaFontaine, Mike

Description:

Amyloid beta (A?), the hallmark of Alzheimer's Disease (AD), now appears to be deleterious in its low number aggregate form as opposed to the macroscopic A? fibers historically seen postmortem. While Alzheimer targets, such as...

Type:

Article
Targeting amyloid precursor protein shuttling and processing - long before amyloid beta formation.

Creator:

Arbor, Sage

Description:

<strong>Targeting early steps in amyloid-beta production:</strong> Alzheimer's disease (AD) has a long history as the “amyloid deposit” disorder. Many disorders are now known to be caused by protein ?-sheet misfolding and...

Type:

Article