There are limited data regarding the level of research experience and/or interest among osteopathic medical students despite a rapidly increasing enrollment and expansion of the number of osteopathic medical schools. A 2016...
Insulin resistance is associated with a high cumulative risk of AD and reduced cerebral glucose metabolism. New data suggest that increased hexosamine biosynthesis pathway (HBP) activity induces insulin resistance in adipose...
Context: We aimed to determine the availability of price estimates from hospitals in the United States for a pediatric orthopaedic surgical procedure (closed reduction and pinning of a distal radius fracture), and identify...
Osteoporosis, a disease of low bone mineral density, affects 10 million Americans and triggers significant health problems and considerable socioeconomic burdens. Current treatments for osteoporosis have significant...
Osteoporosis is a disease of low bone mass resulting from bone resorption exceeding bone formation that places individuals at enhanced risk for fracture, disability, and death. There is an urgent and unmet need for novel...
The over accumulation of misfolded protein aggregates is a key contributor in neurodegeneration associated with diseases such as Alzheimer’s, Parkinson’s, Huntington’s disease, and Amyotrophic Lateral Sclerosis (ALS). In a...
Context. Metabolic syndrome (MetS) refers to the combination of abdominal obesity, hyperglycemia or insulin resistance, dyslipidemia, and hypertension. MetS has been associated with morbidity and mortality after a variety of...
Mechanical loading is critical for bone remodeling. Voltage sensitive calcium channels (VSCCs) influence bone development and responses to loading. The α<sub>2</sub>δ<sub>1</sub> VSCC subunit regulates osteocyte...
Introduction: According to the Centers for Disease Control and prevention (CDC), ensuring student access to needed physical and mental health care improves attendance, behavior, and achievement in the classroom. Academic...
Current therapies for low bone mass consist of inhibiting osteoclast activity or increasing the PTH or Wnt signaling pathways. These approaches have significant drawbacks that limit their use in specific patient populations...