The COVID-19 pandemic has highlighted the need for additional health precautions in medically fragile populations. COVID-19 is a respiratory virus demonstrating increased mortality in individuals with risk factors such as...
During the undergraduate Nursing Research and Informatics course, a question is posed and students are asked to submit a picture with caption that answers the question. All pictures are de-identified, printed, and given to...
Hiatal hernias are a very common medical condition and present as the pathologic passage of the foregut through the esophageal hiatus. While most hiatal
hernias are asymptomatic, presenting symptoms can easily progress to...
Osteoporosis is a disease of low bone mass that places individuals at enhanced risk for fracture, disability, and death. Hospitalizations for osteoporotic fractures exceeds those for heart attack, stroke, and breast cancer...
Strabismus “squint eyes” is a common disorder presenting in about 2% of children born each year. While there are several causes to this presentation, we demonstrated presentation caused by Peripheral nerve neuropathies,...
Obesity and metabolic dysfunction negatively impacts many tissues, including the skeleton. Calcium/calmodulin-dependent protein kinase kinase 2 (CaMKK2) is a serine/threonine protein kinase and key regulator of whole-body...
There is a need for anabolic therapies to treat degenerative bone
diseases. Mechanical loading stimulates anabolic and inhibits
catabolic pathways of bone leading to increased bone formation.
Osteocytes are the bone cell...
Purpose: Partial nephrectomies by their nature are associated with renal volume loss. Our goal from this study is to examine renal volume loss over time post partial nephrectomy.
Material and Methods: Fifty patients were...
Correlations exist between undergraduate GPA,
MCAT, and COMLEX-USA Level 1 scores as well as
between course grades and overall COMLEX score
(Wong et al. 2009 & Sefcik et al. 2003).
• Longitudinal reports on ProgressIQ...
Background: A patent ductus arteriosus (PDA) is a common diagnosis among
extremely preterm infants. Unfortunately, this left to right shunt may result in
significant complications including pulmonary edema, pulmonary...
Why do neurocognitive disorders persist in people living with HIV while taking combination antiretroviral therapy
(cART)?
• The brain is a known reservoir for HIV.
• HIV can act on myeloid cell populations like...
Atlantoaxial instability (AAI) is a term that is used to describe instability at the atlantoaxial joint of the cervical spine. This is often from alar ligament instability causing the dens of the axis to be prone to move...
Ticks have been widely studied for their importance in disease transmission. In
Pennsylvania, four different ticks (associated with human diseases) are commonly
encountered: (1) Dermacentor variabilis (Rocky Mountain Spotted...
The dramatic increase in the prevalence of antibiotic resistant (AR) genes
in numerous bacterial species has been a heavily discussed topic within
the scientific community. Antibiotic resistant bacteria pose a serious
threat...
Menopause, an age-related loss of sex hormone production in women, is one of the most common causes of osteoporosis. Previous work has established that this loss of sex hormones, in particular estrogen, causes dramatic loss of...
1.5 million reported traumatic brain injuries (TBI) per year with varying degrees of severity that inflict injury at the cellular level. The Choroid Plexus (CP) plays a significant role in brain homeostasis. The CP has also...
The United States Preventative Services Task Force (USPSTF) recommends initiating colorectal cancer screening for asymptomatic, average-risk individuals at age 45, which is a new update to the previous recommendation of age 50....
Background: Many patients seek the advise from their primary care providers (PCPs) to provide insight into alternative treatment options, however, little is known about the practices of primary care providers (PCPs) and the...
Background: A child’s pain is different from pain experienced as adults. Different emotional and psychological factors can affect the child’s pain comprehension and stimulate their response to pain. Procedural pain can have...
Background and Review of Literature: A surgical site infection after posterior instrumented spinal fusion can negatively affect the patient and increase healthcare costs. Spinal fusions are becoming increasingly common as a...
In 1984, Ultrasound-Guided (USG) Intravenous (IV) access was first used to place central venous catheters (CVC) in real-time. This led to increased success rates, reduced procedural times, decreased site associated...
Traditionally, the acute wrist radiograph series is comprised of
posteroanterior (PA), oblique, and lateral projections. There is controversy within the field of Orthopedics, however, over the value of the oblique view in...
• Myroides spp. are non-motile, aerobic, gram-
negative bacilli that are traditionally
opportunistic pathogens1.
• P. stuartii is a urease-producing, gram-negative
bacillus2.
• Myroides infections have been reported
60...
Calcitriol is a vitamin critical in regulating calcium
homeostasis, maintenance of musculoskeletal
integrity, and both a commonly prescribed medication
and over the counter supplement.
• However, the incidence of vitamin D...
Children with acute lymphoblastic leukemia
(ALL) suffer a litany of therapy induced side
effects. Methotrexate is a common chemotherapy agent
administered for the treatment of ALL. Failure to clear methotrexate from the body...
Multiple sclerosis (MS), one of the most
prevalent immune-mediated neurological
disorders, is a chronic demyelinating disease
of the central nervous system that affects both
white and grey matter (Avasarala et....
3D visualization software is a useful tool in
patient education because it allows patients to
put an image to what a physician is describing
to them. With an emphasis on education of
young athletes on the potential...
Klotho is a regulatory anti-aging protein that is significantly expressed
in the choroid plexus, plays an important role in regulating the immune
response in the CNS, and diminishes with age. Klotho deficiency is...
Kisspeptin together with its receptor, GPR54 (Kiss1R), are known for their function as the principal regulators of the onset of mammalian puberty. Given the characteristic growth spurt and bone development that occurs during...
Due to the availability of information on the internet, patients are well informed of the several types of hernia repair available to them. They are also increasingly made aware of the litigious environment surrounding...
Chlamydia trachomatis (Ct) is the most common bacterial sexually transmitted pathogen and is a significant threat to the reproductive health of women. With an estimated 2.8 million new infections domestically and 131 million...
Recent studies describe racial and socioeconomic
(SES) disparities with mechanical thrombectomy
(MT) for acute ischemic stroke (AIS). Our study
investigated whether such disparities are present at
our institution and...
Nursing Homes (NH) often struggle to provide
Palliative Care (PC) to their residents with Alzheimer’s
and other Related Dementias (ADRDs). As a result,
many NHs are searching for external PC consultants to
help facilitate...
Chemotherapeutic agents, such as vincristine, are well known
antineoplastic and cytotoxic drugs, affecting patients broadly during
treatment of cancer. Well known side effects, such as constipation
and neuropathic pain,...
The COVID-19 pandemic resulted in widespread mRNA vaccinations against SARS-CoV2. Side effects include fatigue, headache, myalgia,
fever, nausea, and lymphadenopathy, frequently experienced in younger recipients (16-55 years)...
Antibiotic resistance is not only a major threat to public health, with more than
700,000 deaths per year, but also has serious economic impacts.1 Nosocomial-
acquired antibiotic-resistant infections have well-established...
Bitter melon extract (BME) is known to inhibit breast cancer cells (MCF-7) proliferation. Due to the high metabolic rate of cancer cells, we hypothesized that low glucose levels are detrimental to cell survivability and that...
Malignant mesothelioma typically presents in patients with asbestos exposure, with respiratory symptoms caused by primary pleural involvement with associated pleural effusion. Instead, this patient presented with a rapidly...
Older adults (65+) are at an increased risk of contracting COVID-19 and have higher incidences of adverse events. Nursing home residents are particularly vulnerable due to congregate living and the need for personal care. CMS...
Ambulances are a target for theft and reportings of ambulance thefts has been increasing in the past several years. There is a paucity of research in this area, as a PubMed search of the terms ambulance theft yields only one...
Rubella was first described in the 1750s but took until 1941 when Congenital Rubella Syndrome was characterized to become medically significant. Similarly, zika virus was discovered in 1947 but only made headlines in 2016 when...
Reported cases of isolated fetal ascites determined to be idiopathic have been shown to carry a favorable prognosis with frequent spontaneous resolution in utero (1,2,3). These cases generally reported better fetal outcomes...
Over 1.25 million people reside in nursing facilities in the United States. Nursing facilities have reported 268,707 confirmed cases of COVID-19 and 61,765 COVID-19 deaths as of the week of November 2, 2020. Indiana was one of...
Osteoporosis is a silent, dangerous pathology frequently undiagnosed until patients experience a major fracture. About 1 in 2 women and 1 in 4 men ages 50 and above will experience bone fractures due to osteoporosis. Fractures...
Healthcare disparities among different racial and ethnic groups are prevalent across the United States and worldwide. Healthcare provision may differ among racial and ethnic minorities, socioeconomic statuses, and insurance...
The ability to communicate with patients effectively continues to be a major hindrance for physicians and physician offices. Coordinating care via conventional telecommunication, involving making calls to a healthcare facility...