3D visualization research is useful as a learning tool for medical students learning human anatomy and as a diagnostic tool for practicing physicians. Here we explore the use of this application of medical imaging in...
Background: Transposition of the Great Vessels (TGV) is a congenital heart defect (CHD) in which the great vessels are reversed – the aorta arises off of the right ventricle and the pulmonary trunks arises off the left...
We sought to evaluate a novel PPARδ inhibitor and explore whether this compound could synergize with known chemotherapeutic compounds to kill cancer cells in culture. Methods: A novel PPARδ inhibitor compound, Compound 9, was...
Unemployment is a substantial problem amongst veterans with mental illness. This pervasive vocational dysfunction results in poor financial, clinical, quality of life, and psychosocial outcomes. The Cognitive Behavioral Therapy...
Fibroblast growth factor-23 (FGF23) controls key responses to systemic phosphate increases through its phosphaturic actions on the kidney. In addition to stimulation by phosphate, FGF23 positively responds to iron deficiency...
The Activin and BMP signaling pathways exert reciprocal effects on myogenesis and skeletal muscle regeneration after injury. Signal transduction in both pathways is mediated by ligand- induced activation of transcriptional...
Over the past twenty years, opioid drug use has increased, causing an epidemic of opioid abuse that is killing tens of thousands of people every year. Current treatment options for opioid abuse disorder include alternative...
Objective: A proof-of-concept for a platform designed to provide simulations modeling, in three dimensions, anatomical pathology/dysfunctions(as defined by osteopathic diagnostic criteria). Design/Methods: Data from a two...
Antibiotic resistance has remained a topic of concern, and most current treatments prioritize preventing infections from antibiotic resistant pathogens. Hence, finding new antimicrobial compounds to suppress or rid of pathogens...
Diabetic ketoacidosis (DKA) is a life threatening complication of type 1 diabetes (T1D) resulting from ketone body production and metabolic acidosis occurring due to insulin deficiency, We sought to define the occurrence of DKA...