Post-pandemic, some educators are trying to reengage students with technology – like videos, computer gaming or artificial intelligence, just to name a few. But integrating these approaches in the classroom can be an uphill...
Orientia tsutsugamushi, the etiologic agent of the life-threatening febrile disease scrub typhus, is an obligately intracellular small coccobacillary bacterium belonging to the family Rickettsiaceae and is transmitted by the...
More than 200 heterozygous mutations in the type 2 BMP receptor gene, BMPR2, have been identified in patients with Heritable Pulmonary Arterial Hypertension (HPAH). More severe clinical outcomes occur in patients with BMPR2...
Despite numerous advances, the 5-year survival rate for head and neck squamous cell cancer (HNSCC) has remained largely unchanged. This poor outcome is due to several variables, including the development of multiple primary...
Specifically in the medical field, Catholic providers rarely receive extensive education regarding the applications of moral theology to their work. Those knowledgeable on the topic have often gone to great lengths to acquire...
Involvement in research is regarded as a high-impact educational practice, which, for medical professionals, is associated with sharpened critical thinking and life-long learning skills, greater appreciation for evidence-based...
Obesity is accompanied by numerous systemic and tissue-specific derangements, including systemic inflammation, insulin resistance, and mitochondrial abnormalities in skeletal muscle. Despite growing recognition that adipose...
50% improved maximal aerobic capacity (VO2max) and enhanced skeletal muscle health (size, function, as well as metabolic and communicative properties) compared to non-exercisers at a similar age. By taking a reductionist...
Amyloid beta (A?), the hallmark of Alzheimer's Disease (AD), now appears to be deleterious in its low number aggregate form as opposed to the macroscopic A? fibers historically seen postmortem. While Alzheimer targets, such as...
Aristotle identifies four modes of unity: numerical, specific, generic, and proportional or analogous. Recent scholarship has renewed the Renaissance and early Modern Thomist critique that John Duns Scotus's (d. 1308) doctrine...
At the beginning of his influential De Nominum Analogia, Thomas de Vio Cajetan (1469–1534) mentions three mistaken positions on analogy. He does not attach names to these positions, but each one was held by distinguished...
The internal jugular veins (IJV) are the primary venous outflow channels of the head and neck. The IJV is of clinical interest since it is often used for central venous access. This literature aims at presenting an overview of...
Lymphangiogenesis is an essential physiological process but also a determining factor in vascular-related pathological conditions. Angiopoietin-2 (Ang2) plays an important role in lymphatic vascular development and function and...
Embedding carbon in metals has long been known to enhance the mechanical properties of metal carbon composites. We report the possibility of growing Al–C composites by the hot isostatic pressing method, with carbon embedded...
Background: A sterile surgical marking pen is commonly used during anterior cruciate ligament reconstruction (ACLR) to outline the proposed skin incision and then to mark the graft during preparation. Once in contact with the...
Castor canadensis Kuhl (North American beavers) are central place foragers who<br />collect woody plants and building materials from their surroundings and return to a main body of water containing a lodge or food cache. It has...
Breast cancer is one of the most commonly diagnosed cancers among women, however the complete cure for metastatic breast cancer is lacking due to poor prognosis. There has been an increasing trend of dietary modifications...
Bone morphogenetic proteins (BMPs) constitute the largest subdivision of the transforming growth factor-? family of ligands. BMPs exhibit widespread utility and pleiotropic, context-dependent effects, and the strength and...
Genetic and functional studies indicate that common components of the bone morphogenetic protein (BMP) signaling pathway play critical roles in regulating vascular development in the embryo and in promoting vascular homeostasis...
The bone morphogenetic protein (BMP) type 2 receptor ligand, Bmp2, is upregulated in the peripheral pulmonary vasculature during hypoxia-induced pulmonary hypertension (PH). This contrasts with the expression of Bmp4, which is...
Enhancing bone morphogenetic protein (BMP) signaling increases bone formation in a variety of settings that target bone repair. However, the role of BMP in the maintenance of adult bone mass is not well understood. Targeted...
Initiation of BMP signaling is dependent upon activation of Type I BMP receptor by constitutively active Type II BMP receptor. Three Type II BMP receptors have been identified; Acvr2a and Acvr2b serve as receptors for BMPs and...
Bone morphogenetic proteins (BMPs) constitute the largest subdivision of the transforming growth factor (TGF)-? family of ligands and exert most of their effects through the canonical effectors Smad1, 5, and 8. Appropriate...
Bone morphogenetic proteins (BMPs) constitute the largest subdivision of the transforming growth factor (TGF)-? family of ligands and exert most of their effects through the canonical effectors Smad1, 5, and 8. Appropriate...
Note: supplemental powerpoint slides available below. and OBJECTIVES: Arch branching has never been shown to influence recoarctation after extended end-to-end anastomosis via thoracotomy, yet in each study bovine arch...
Osteoporosis, a disease of low bone mass, places individuals at enhanced risk for fracture, disability, and death. In the USA, hospitalizations for osteoporotic fractures exceed those for heart attack, stroke, and breast cancer...
In this poster, I will show how German students at Marian have engaged with members of the local German community and how this has impacted their learning. and Presented in the Global Learning track.
Osteoblasts and bone marrow adipocytes originate from bone marrow mesenchymal stem cells (BMMSCs) and there appears to be a reciprocal relationship between adipogenesis and osteoblastogenesis. Alterations in the balance between...
NOL7 is a putative tumor suppressor gene localized to 6p23, a region with frequent loss of heterozygosity in a number of cancers, including cervical cancer (CC). We have previously demonstrated that reintroduction of NOL7 into...
This article addresses Christian discipleship: (1) as a primordial model for comprehensive Catholic youth ministry and (2) as a developmental theology for contemporary youth ministry. Moreover, it situates Christian...
Sudangrass [ Sorghum sudanense (Piper) Stapf] is a hybrid between grain sorghum and its wild relative S. bicolor ssp. verticilliflorum and is grown as a forage crop due to its high biomass production and low dhurrin content...
Providing safe and effective care is identified by the Quality and Safety Education for Nurses (QSEN) guidelines as an essential competency (QSEN, www.qsen.org). First semester nursing students are challenged to evaluate their...
The plant-specific TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL FACTOR (TCP) transcription factor family is most closely associated with regulating plant developmental programs. Recently, TCPs were also shown to mediate host...
The transforming growth factor ? (TGF-?) superfamily is a large group of signaling molecules that participate in embryogenesis, organogenesis, and tissue homeostasis. These molecules are present in all animal genomes....
The Bone Morphogenetic Protein (BMP) pathway is a multi-member signaling cascade whose basic components are found in all animals. One member, BMP3, which arose more recently in evolution and is found only in deuterostomes,...
This experiment analyzes three different techniques used in literature to detect cytokine release from cells in vitro: the Human Cytokine Array (HCA) by R&D Systems, the BD Cytometric Bead Array (CBA) assay, and protein...
The national self-images of the United States and Canada have been shaped, in part, by their contrasting histories and mythologies of westward expansion and nation-building. Those narratives are most distinct with regard to...
In 1966, David Baker, a Black man and esteemed jazz musician and composer, created and developed the Jazz Studies program at Indiana University (IU). The purpose of this study was to investigate how David Baker came to join the...
Gender dysphoria [GD] or a sex and gender discord that leads to enormous psychological suffering in some variants of transgender people is a highly complex and debatable subject. Muslim culture, religious and ethical values...
Agglomeration of active pharmaceutical ingredients (API) in tablets can lead to decreased bioavailability in some enabling formulations. In a previous study, we determined that crystalline APIs can be detected as...
We conducted a study of the diet of the federally endangered Indiana bat (Myotis sodalis) at an urban/rural interface near Indianapolis International Airport in summer 2004. We used two 1-m2quadrats covered with window...
This article considers the attempt by a prominent fifteenth-century follower of Thomas Aquinas, Dominic of Flanders (a.k.a. Flandrensis, 1425-1479), to address John Duns Scotus’ most famous argument for the univocity of being....
OBJECTIVES: The diagnosis of cervical lymph node metastasis in head and neck squamous cell carcinoma (HNSCC) patients constitutes an essential requirement for clinical staging and treatment selection. However, clinical...
Despite recent therapeutic advances, several factors, including field cancerization, have limited improvements in long-term survival for oral squamous cell carcinoma (OSCC). Therefore, comprehensive treatment plans must include...
Successful fracture healing requires the simultaneous regeneration of both the bone and vasculature; mesenchymal stem cells (MSCs) are directed to replace the bone tissue, while endothelial progenitor cells (EPCs) form the new...
Background
Precise public health and clinical interventions for the COVID-19 pandemic has spurred a global rush on SARS-CoV-2 variant tracking, but current approaches to variant tracking are challenged by the flood of viral...
Conflict can have detrimental effects on team interaction, performance, and member satisfaction, so research on tools and techniques aimed at reducing or resolving conflict is crucial. This study trained the leaders of teams...
Found in Advances in Microbiology, https://www.scirp.org/pdf/aim_2020082015540201.pdf and Background: Farnesol is added to numerous consumer products that intentionally, or inadvertently come in contact with tissues that may...
Background: Farnesol is added to numerous consumer products that intentionally, or inadvertently come in contact with tissues that may harbor the opportunistic yeast, Candida albicans. Objective: This study explores biological...
Objective
Many C. elegans aging studies use the compound 5-fluro-2ʹ-deoxyuridine (FUdR) to produce a synchronous population of worms. However, the effects of FUdR on the bacterial gene expression of OP50 E. coli, the primary...
Keeping pace with the rapid advance of library technology and electronic services can be both exciting and daunting, especially for libraries with a small (but mighty!) staff. Out of necessity, small staffs often undertake many...
Imbalanced angiogenesis is a characteristic of several diseases. Rho GTPases regulate multiple cellular processes, such as cytoskeletal rearrangement, cell movement, microtubule dynamics, signal transduction and gene...
Background: In order to become safe, effective professionals, nursing students must have a working knowledge of academic and professional integrity principles. However, nursing students have knowledge gaps in these areas, which...
G-protein coupled receptors (GPCRs), which activate heterotrimeric G proteins, are an essential class of transmembrane receptors that are responsible for a myriad of signaling events in normal and pathologic conditions. Two...
Behavioural responses to communicative signals combine input from multiple sensory modalities and signal compensation theory predicts that evolutionary shifts in one sensory modality could impact the response to signals in...
Purpose: This case report aims to explore a rare combination of findings in a cadaver donor: variant ansa cervicalis, vagus (CN X) and hypoglossal (CN XII) nerve fusion, and extracranial hypoglossal neurofibroma.
Background:...
Dorsal markings are common, and can function in predator evasion, as sexual signals, or be the remnants of developmental or physiological processes. We used phylogenetic comparative analyses to test whether black dorsal...
The gene CHEK2 is located at 22q12.1 and codes for the protein checkpoint kinase 2, a protein that functions in cell cycle regulation and is a known tumor suppressor. CHEK2 is activated due to DNA damage generating a cascade of...
Gender dysphoria (GD), a conflict between one's self-perceived gender identity and the biological sex has been a wholly enigma
and a source of contention between experts of various disciplines since long. This is a narrative...
Head and neck squamous cell carcinomas (HNSCC) often metastasize to locoregional lymph nodes, and lymph node involvement represents one of the most important prognostic factors of poor clinical outcome. HNSCCs are remarkably...
Transposable elements (TEs) are sequences that replicate and move throughout genomes, and they can be silenced through methylation of cytosines at CpG dinucleotides. TE abundance contributes to genome size, but TE silencing...
BACKGROUND: The Trauma Quality Improvement Program was designed by the American College of Surgeons to measure quality benchmarks across American College of Surgeons-certified trauma centers. The Hospital Consumer Assessment...
Bone morphogenetic protein (BMP) signaling has been linked to the development of pulmonary hypertension (PH). Inhibitors of differentiation (ID) proteins (ID1-4) are a family of basic helix-loop-helix transcription factors that...
BACKGROUND: NOL7 is a candidate tumor suppressor that localizes to a chromosomal region 6p23. This locus is frequently lost in a number of malignancies, and consistent loss of NOL7 through loss of heterozygosity and decreased...
Originally appearing in BMC Research Notes as an open access article under the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/)., The bone morphogenetic protein (BMP)...
The bone morphogenetic protein (BMP) signaling pathway comprises the largest subdivision of the transforming growth factor (TGF?) superfamily. BMP signaling plays essential roles in both embryonic development and postnatal...
Friedreich ataxia (FRDA) is an autosomal recessive neuro- and cardio-degenerative disorder caused by decreased expression of frataxin, a protein that localizes to mitochondria and is critical for iron-sulfur-cluster (ISC)...
Friedreich ataxia (FRDA) is an autosomal recessive neuro- and cardio-degenerative disorder caused by decreased expression of frataxin, a protein that localizes to mitochondria and is critical for iron-sulfur-cluster (ISC)...
Friedreich ataxia (FRDA) is an autosomal recessive neuro- and cardio-degenerative disorder caused by decreased expression of frataxin, a protein that localizes to mitochondria and is critical for iron-sulfur-cluster (ISC)...
Ceramide glucosyltransferase (CGT) adds sugar moieties to ceramide, forming glucosylceramides that play roles in immune signaling, stress response, and host-bacterial interactions. Here, we examined whether mutations in cgt...
Re-epithelialization after cutaneous injury is a complex and multifaceted process that incorporates numerous cellular components interacting in a myriad of pathways. One of the most crucial aspects of this process is the...
Patients with familial pulmonary arterial hypertension inherit heterozygous mutations of the type 2 bone morphogenetic protein (BMP) receptor BMPR2. To explore the cellular mechanisms of this disease, we evaluated the pulmonary...
Colorful ornaments are important visual signals for animal communication that can provide critical information about the quality of the signaler. In this study, we focused on different color characteristics of the abdominal...
Virtual microscopy podcasts (VMPs) are narrative recordings of digital histology images. This study evaluated the outcomes of integrating the VMPs into teaching histology to osteopathic medical students. The hypothesis was that...
Background We present 3 likely cases of testicular dysgenesis syndrome (TDS) within a community of chimpanzees (<em>Pan troglodytes schweinfurthii</em>). We tested whether genetic drift may be the culprit, as a genetic cause...
The writings of John Capreolus (ca. 1380-1444), the Prince of Thomists, have come down to us exclusively through his great work, the Defense of the Theology of Thomas Aquinas (abbreviated in this article as the Defensiones),...
Klotho is a regulatory anti-aging protein that is significantly expressed in the choroid plexus, plays an important role in regulating the immune response in the CNS, and diminishes with age. It is known that a decline of...
Context: Regional conservation efforts should incorporate fine scale landscape genetic and habitat suitability data for management decisions. This information permits conservation measures to be tailored to a specific...
Context: Regional conservation efforts should incorporate fine scale landscape genetic and habitat suitability data for management decisions. This information permits conservation measures to be tailored to a specific...
Part of special issue: Women in Topology III. Abstract: We develop a spectral sequence for the homotopy groups of Loday constructions with respect to twisted cartesian products in the case where the group involved is discrete....
Loeys-Dietz syndrome (LDS) is a connective tissue disorder that commonly results in a dilated aorta, aneurysms, joint laxity, craniosynostosis, and soft skin that bruises easily. Neurodevelopmental abnormalities are uncommon in...
Imbalances in the ratio of bone morphogenetic protein (BMP) versus activin and TGF? signaling are increasingly associated with human diseases yet the mechanisms mediating this relationship remain unclear. The type 2 receptors...
The taste receptor type 1 (TAS1R) family of heterotrimeric G protein-coupled receptors participates in monitoring energy and nutrient status. TAS1R member 3 (TAS1R3) is a bi-functional protein that recognizes amino acids such...
The White-tailed Ptarmigan (<em>Lagopus leucurus</em>) is one of the few socially monogamous species within the highly polygynous grouse subfamily (Tetraoninae). I found White-tailed Ptarmigan in Glacier National Park, Montana,...
Purpose: Malnutrition and cachexia during pediatric cancer treatment worsen toxicity and quality-of-life. Clinical practice varies with lack of standard malnutrition definition and nutrition interventions. This systematic...
For students taking higher level mathematics courses, the transition from computational to proof-based courses such as analysis and algebra not only introduces a new format of writing and communication, but also a new level of...
Context: It is important for colleges of osteopathic medicine (COMs) to provide opportunities for osteopathic medical students (OMSs) to conduct research under the guidance of professional researchers. However, COMs...
The authors present a stereotypical case presentation of X-linked hypophosphatemia (XLH) and provide a review of the pathophysiology and related pharmacology of this condition, primarily focusing on the FDA-approved medication...
AIMS: Recent studies have suggested a possible association between microbiota and gestational diabetes (GDM). However, the results are inconsistent. Our objective was to investigate further the relationship between GDM and...
BACKGROUND: We examined the short- and long-term efficacy and tolerability of a cross-titration algorithm from oral dopamine agonists to the rotigotine transdermal patch in patients dissatisfied with their restless legs...
This article evaluates the current Catholic youth ministry practice to, with, and for Catholic LGBTQ youth. The methodology utilized is both descriptive and prescriptive, and calls into question the lack of ministerial presence...
Several significant aspects are addressed in this article to gain clarity and to pursue awareness regarding transgender teenagers. It begins by offering a brief introduction and then moves towards a common understanding of the...
This article considers the ministry and pastoral care to transgender teenagers. It begins by offering a brief introduction and then concentrates on the ways or methods for providing pastoral care, support, and advocacy to...
This article reviews recent progress in the design and theoretical investigation of molecular implementations of quantum-dot cellular automata (QCA) for field-coupled nanocomputing applications. QCA is a classical computing...